Kathryn E. Beckermann, MD, PhD

Kathryn E. Beckermann, MD, PhD, is an assistant professor in the Department of Medicine of the Division of Hematology and Oncology at the Vanderbilt School of Medicine in Nashville, Tennessee.

Articles

RCC Treatment Evolution: Expert Perspectives on the Evolving Landscape and Advances From ASCO GU 2025

March 21st 2025

Experts discuss how treatment sequencing in advanced renal cell carcinoma (RCC) may evolve with the emergence of novel combinations and highlight emerging data from ASCO GU 2025 likely to impact clinical practice.

Emerging Therapies in RCC: Shaping Future Treatment Sequences

March 21st 2025

Experts discuss the role of belzutifan and tivozanib in the treatment paradigm for advanced renal cell carcinoma (RCC), including key findings from the phase 3 LITESPARK-005 trial investigating belzutifan vs everolimus in previously treated advanced RCC patients.

Post-Immunotherapy Options in RCC: Latest Trial Data and Expert Perspectives on Rechallenge Strategies

March 21st 2025

Experts discuss key findings from the phase 3 CONTACT-03 trial investigating atezolizumab plus cabozantinib vs cabozantinib alone in inoperable advanced renal cell carcinoma (aRCC) after immune checkpoint inhibitor (ICI) treatment, along with insights from real-world data on sequencing strategies and the efficacy of tyrosine kinase inhibitors (TKIs) after prior ICI therapy.

Navigating RCC Progression: Optimizing Treatment Sequence After the First Line

March 14th 2025

Experts discuss emerging patterns of progression with current frontline regimens for advanced renal cell carcinoma (RCC), differences between immunotherapy (IO)/IO and IO/tyrosine kinase inhibitor (TKI) combinations, and how these progression patterns impact prognosis and subsequent therapy selection, considering whether the patient received IO/IO or IO/TKI in the first line and the clinical factors influencing later-line treatment decisions.

Optimizing IO/TKI Success: Managing Adverse Effects and Personalizing Treatment

March 14th 2025

Experts discuss regimens with the most favorable toxicity profiles and how they personalize treatment to minimize patient burden, while also exploring preferred strategies for patients who have completed pembrolizumab in the adjuvant setting and how the timing of recurrence relative to adjuvant therapy completion influences treatment selection.

RCC Treatment Selection: Expert Perspectives on Long-Term Data and Insights on Treatment Selection

March 7th 2025

Experts discuss key factors influencing the decision between immunotherapy (IO)/IO and various IO/tyrosine kinase inhibitor (TKI) combinations in advanced renal cell carcinoma (RCC) treatment, including patient characteristics, risk stratification, PD-L1 status, and other clinical features, while also exploring the patient experience with IO-TKI regimens, strategies for managing adverse effects, and the approach to hepatotoxicity management.

Long-Term Data From CheckMate 9ER Investigating Nivolumab Plus Cabozantinib in Untreated Advanced RCC

March 7th 2025

Experts discuss the key findings from the final follow-up results of the CheckMate 9ER trial, evaluating nivolumab plus cabozantinib in advanced renal cell carcinoma (RCC) and share perspectives on the clinical implications of these updated data, along with insights from other studies of note, including LITESPARK-003 (belzutifan plus cabozantinib) and LITESPARK-024 (belzutifan plus palbociclib).

Dr Beckermann on the Role of Tivozanib in Advanced Clear Cell RCC

February 28th 2025

Kathryn E. Beckermann, MD, PhD, details the role of tivozanib as second- and third-line therapy in patients with locally advanced or metastatic ccRCC.

Optimizing IO-TKI Selection: Patient-Specific Approaches for Optimal Outcomes

February 28th 2025

Experts discuss how emerging novel doublet regimens in the frontline setting for advanced renal cell carcinoma may address current unmet needs, highlighting specific biomarkers, patient populations, and clinical scenarios where these combinations could offer distinct advantages over existing standards like immunotherapy (IO)/IO or established IO/tyrosine kinase inhibitor (TKI) combinations.

Long-Term Outcomes in Advanced RCC: Analyzing 8 Years of CheckMate 214 Data

February 28th 2025

Experts discuss the 8-year follow-up data from the CheckMate 214 trial evaluating nivolumab plus ipilimumab for first-line treatment of advanced renal cell carcinoma (RCC), and how these mature overall survival (OS) data influence the view of nivolumab plus ipilimumab as a frontline option, alongside insights from efficacy, safety, post hoc subgroup analyses (Albiges et al, Eur Urol, 2022), and health-related quality of life (HRQOL) data (Cella et al, J Clin Oncol, 2022).

Dr Beckermann on Targeting TREM2 in the Treatment of ccRCC

May 7th 2024

Kathryn Beckermann, MD, PhD, discusses ongoing studies investigating the role of TREM2 in the treatment of patients with clear cell renal cell carcinoma.

Dr Beckermann on the Investigation of PY314 Plus Pembrolizumab in ccRCC

February 20th 2024

Kathryn Beckermann, MD, PhD, discusses the treatment of PY314 in combination with pembrolizumab in patients with clear cell renal cell carcinoma.

Genetic Counseling for Patients with Non-Clear Cell RCC

April 26th 2023

The panel closes their discussion with a look at the standards for genetic counseling for patients with non-clear cell RCC.

Best Approaches and Emerging Data in the Treatment of Non-Clear Cell RCC

April 26th 2023

The panel discusses the best approaches to treating patients with non-clear cell RCC.

Preferred Treatment Regimens for Refractory RCC

April 19th 2023

The panel shares their preferred treatment regimens for patients with refractory renal cell carcinoma.

Patient Profile Presentation: A 47-Year-Old Male With Refractory RCC

April 19th 2023

Hans Hammers, MD, presents a profile of a 47-year-old male with refractory renal cell carcinoma.

Updates in the Adjuvant Treatment of Metastatic RCC

April 12th 2023

The panel discusses recent clinical trial data in the adjuvant treatment of metastatic renal cell carcinoma.

Reviewing Data in Frontline Metastatic RCC Treatment from the COSMIC-313 Trial

April 5th 2023

Drs Moshe Ornstein and Hans Hammers review data from the COSMIC-313 trial investigating ipilimumab, nivolumab, and cabozantinib for the frontline treatment of metastatic renal cell carcinoma.

Novel Doublet Combination Therapies in First-Line Metastatic RCC Treatment

April 5th 2023

The panel provides an overview of novel double combination therapies currently under investigation.

Treatment Approaches for Patients with RCC and Bone Metastases

March 31st 2023

Mehmet Asim Bilen, MD, details how he approaches IO/TKI therapy for patients with renal cell carcinoma with bone metastases.