Othman Al-Sawaf, MD

Articles

Reflections and Future Directions in CLL Management

February 17th 2025

Panelists comment on the increasing preference for fixed-duration therapy over treatment until progression, as reflected in recent guideline updates.

Emerging Agents and Future Strategies in Relapsed/Refractory CLL

February 17th 2025

Panelists discuss the role of non-covalent BTKis in this setting and available supporting data (high level).

Progression on BTK Inhibitors: Treatment Options and Considerations

February 10th 2025

Panelists comment on the role of combination venetoclax-ibrutinib in this setting and available supporting data.

Relapse After Venetoclax-Based Therapy: Early vs Late Management

February 10th 2025

Panelists review recent ESMO guideline updates for managing early relapse after venetoclax-based time-limited therapy, managing relapse after chemoimmunotherapy or late relapse after venetoclax-based time-limited therapy and defining early versus late relapse.

Exploring Novel BCL2i and BTKi Combinations in Frontline CLL Therapy

February 3rd 2025

Panelists discuss the ongoing trials evaluating other BCL2i/BTKi combination approaches.

Managing CLL with TP53 Mutation or del(17p): Guidelines and Strategies

February 3rd 2025

Panelists review recent ESMO guideline updates for the frontline management of patients with CLL and a TP53 or del(17p) mutation.

Comparing Venetoclax-Ibrutinib, Venetoclax-Obinutuzumab, and BTKi Options

January 27th 2025

Panelists discuss the role of ven-ibr in patient populations.

Doublet Therapy With Venetoclax-Ibrutinib: Data and Guidelines

January 27th 2025

Panelists discuss the addition of doublet venetoclax-ibrutinib as a treatment option in ESMO guideline updates.

Clinical Insights and Real-World Evidence

January 24th 2025

Panelists discuss, which patients are favored for the Venetoclax-Obinutuzumab treatment approach.

Time-Limited Therapy with Venetoclax-Obinutuzumab: Rationale and Data

January 24th 2025

Panelists discuss, role of time-limited therapy with venetoclax-obi in this setting, highlighting the underlying rationale and data supporting this approach.

Implications of ESMO Guidelines for IGHV-Mutated vs Unmutated CLL Patients

January 15th 2025

A panel of medical experts provides an overview of recent ESMO guideline updates on frontline management for patients with IGHV-mutated or unmutated chronic lymphocytic leukemia (CLL) without TP53 mutations, highlighting key clinical implications.

Tailoring Treatment Approaches for Fit vs Unfit CLL Patients

January 8th 2025

A panel of medical experts continues their discussion surrounding an array of treatment options for CLL.

Recent Guideline Updates in the Frontline Management of CLL

January 6th 2025

Dr Niemann provides an overview of the evolving treatment landscape of CLL.

Dr. Al-Sawaf on the Benefit of Fixed-Duration Obinutuzumab/Venetoclax in CLL

August 29th 2022

Othman Al-Sawaf, MD, discusses the benefit of fixed-duration treatment with obinutuzumab plus venetoclax in chronic lymphocytic leukemia.

Dr. Al-Sawaf on the 5-Year Results of the CLL14 Trial in CLL

June 12th 2022

Othman Al-Sawaf, MD, discusses the 5-year follow up data from the phase 3 CLL14 trial (NCT02242942) in patients with previously untreated chronic lymphocytic leukemia (CLL) with preexisting conditions.

Dr. Al-Sawaf on the Efficacy of Venetoclax/Obinutuzumab in Treatment-Naïve CLL

June 11th 2021

Othman Al-Sawaf, MD, discusses the efficacy of venetoclax plus obinutuzumab in patients with chronic lymphocytic leukemia, as demonstrated in the phase 3 CLL14 trial.

Dr. Al-Sawaf on Efforts Examining Venetoclax/Obinutuzumab in CLL

February 24th 2021

Othman Al-Sawaf, MD, discusses research efforts that are evaluating the use of venetoclax and obinutuzumab in patients with chronic lymphocytic leukemia.

Dr. Al-Sawaf on the Next Steps of the CLL14 Trial in CLL

January 4th 2021

Othman Al-Sawaf, MD, a physician with the University Hospital of Cologne in Germany, discusses the next steps of the CLL14 trial in chronic lymphocytic leukemia.

Dr. Al-Sawaf on the Limitations of Continuous Therapy Administration in CLL

December 22nd 2020

Othman Al-Sawaf, MD, discusses the limitations of continuous therapy administration in chronic lymphocytic leukemia.

Dr. Al-Sawaf on New Safety Signals With Venetoclax/Obinutuzumab in the CLL14 Trial

August 4th 2020

Othman Al-Sawaf, MD, discusses new safety signals with venetoclax plus obinutuzumab in the phase 3 CLL14 trial.