Breast Cancer | Specialty

The OncLive Breast Cancer condition center page is a comprehensive resource for clinical news and expert insights on various types of breast cancer, including those that are triple negative, hormone receptor positive, and/or HER2 positive. This page features news articles, interviews in written and video format, and podcasts that focus on treatment advances and ongoing research in breast cancer.

Sledge Expects "Big Data" to Generate Big Changes

May 15th 2013

The technological advances in analyzing the human genome have spawned a new era in breast cancer as well as other types of malignancies that will affect oncology practice and will necessitate dramatic changes in the clinical trials system.

Dr. Chagpar Discusses Sentinel Node Biopsying

May 15th 2013

Anees Chagpar, MD, MSc, MA, MPH, Associate Professor of Surgery (Oncology), Director, The Breast Center at Smilow Cancer Hospital at Yale-New Haven, gives an overview of the discussion surrounding sentinel node biopsying before and after neoadjuvant chemotherapy.

I-SPY Trials Seek Effective New Drug Combinations Using Adaptive Trial Design

May 14th 2013

The I-SPY trials are designed to test several different experimental therapies at once to determine which ones work best in which patients.

Anticipatory and Delayed Nausea Remain Concerns for Patients on Chemotherapy

May 13th 2013

Despite progress in treating chemotherapy-induced nausea and vomiting, especially in the acute phase up to 24 hours after treatment, the condition is still one of the side effects patients fear most.

Dr. Baselga Discusses Fine Tuning Drug Doses

May 13th 2013

JosÃ© Baselga, MD, PhD, Physician-in-Chief, Memorial Sloan-Kettering Cancer Center, discusses the need to fine tune mTOR and PI3K inhibitor doses.

Deciding When Post-Mastectomy Radiation Therapy Is Warranted

May 10th 2013

For appropriate patients, postmastectomy radiation therapy is associated with improved locoregional control and better survival.

Dr. Muss on Using Tools to Evaluate Older Patients

May 9th 2013

Hyman B. Muss, MD, Professor of Medicine, Director of Geriatric Oncology, Lineberger Comprehensive Cancer Center, discusses evaluation tools for treating older patients.

Counseling BRCA, Lynch Carriers on Prophylactic Oophorectomy

May 8th 2013

Due to the high lifetime risk of ovarian cancer and the poor ovarian cancer surveillance options available, women who carry BRCA1 or BRCA2 mutations are advised to remove their ovaries and fallopian tubes by age 40 or when childbearing is complete.

Dr. von Minckwitz on Breast Cancer Responses

May 7th 2013

Gunter von Minckwitz, MD, PhD, discusses the current unsolved medical situation regarding patients with breast cancer who do not respond to treatment.

Dr. Tripathy Reviews Targeted Therapies in Breast Cancer

May 3rd 2013

Debu Tripathy, MD, from the University of Southern California Norris Comprehensive Cancer Center, discusses the targeted therapies that are currently available for the treatment of patients with breast cancer.

Dr. Carey on the Future of Clinical Trial Design

May 2nd 2013

Lisa A. Carey, MD, Professor of Medicine, University of North Carolina at Chapel Hill, discusses the present and future state of clinical trial design.

What Is the Role of Maintenance Therapy in Cancer Care?

May 1st 2013

Experts provide an in-depth look at the treatment strategy in patients with solid tumors, specifically looking at the role of maintenance therapy.

Worldwide Effort Yields Major Advances in Identifying Genetic Risks for Breast, Prostate, and Ovarian Cancer

April 30th 2013

A large, international study has yielded a wealth of new information about genetic alterations that can increase an individual's risk of breast, prostate, and ovarian cancer.

Dr. Esserman on Screening Patients With Higher-Risk DCIS

April 30th 2013

Laura Esserman, MD, MBA, Professor, University of California, San Francisco, discusses screening patients with higher-risk DCIS.

Dr. Pegram on Combining Trastuzumab and Pertuzumab

April 26th 2013

Mark D. Pegram, MD, from the Stanford Cancer Institute, describes the combination of pertuzumab and trastuzumab as a treatment for patients with HER2-positive metastatic breast cancer.

Radiotherapy Increases Risk of Heart Disease in Some Women With Breast Cancer

April 26th 2013

While radiotherapy can be an effective treatment for early-stage breast cancer, incidental irradiation of the heart during treatment may increase the risk of developing ischemic heart disease.

Should Sentinel Lymph Node Biopsy Be Postponed Until After Neoadjuvant Therapy?

April 24th 2013

With increasing use of neoadjuvant chemotherapy in early-stage breast cancer, controversy has erupted regarding the optimal timing of sentinel lymph node biopsy.

Dr. Caudle on Upcoming Breast Cancer Trial Results

April 24th 2013

Abigail S. Caudle, MD, Assistant Professor, Department of Surgical Oncology, Division of Surgery, The University of Texas MD Anderson Cancer Center, gives an overview of two trials in breast cancer.

Tumor Biology Is Critical to Making Chemotherapy Choices

April 23rd 2013

The key to advancements in chemotherapy treatment for patients with metastatic breast cancer most likely will come through a better understanding of their underlying tumor biology.

Dr. Chagpar Discusses Surgery for Metastatic Breast Cancer

April 23rd 2013

Anees Chagpar, MD, MSc, MA, MPH, from the Smilow Cancer Hospital at Yale-New Haven, discusses the evolution of surgery as a treatment for patient with metastatic breast cancer.