Precision Medicine in Oncology® | Specialty

The OncLive Precision Medicine in Oncology® condition center page is a comprehensive resource for clinical news and expert insights on precision-focused approaches in patients with cancer, with gene-targeted tyrosine kinase inhibitors and antibody-drug conjugates, checkpoint inhibitors, tumor-infiltrating lymphocyte therapy, and other tailored treatments. This page features news articles, interviews in written and video format, and podcasts that focus on updates and ongoing research with personalized therapies across solid and hematologic tumors.

A Failure to Communicate: Patients Misunderstand Cancer Genetic Testing

July 30th 2013

Patients diagnosed with cancer today are considered to be genuine partners in all major treatment decisions. Yet, how well do they understand the nature and goals of genetic testing that might be recommended as part of the management of their disease?

Dr. Shaw Compares Crizotinib and Chemotherapy in NSCLC

July 19th 2013

Lead author, Alice T. Shaw, MD, PhD, from the Massachusetts General Hospital, reviews the first published results from a randomized phase III trial investigating crizotinib in patients with ALK-positive non-small cell lung cancer.

UNC Research Leader Sees Multiple Roles, Many Questions in NF-κB Activity

July 17th 2013

Albert S. Baldwin, Jr, PhD, focuses on understanding the regulation and biological functions of NF-κB and its role in disease, particularly in cancer, in a laboratory he heads at the UNC Lineberger Comprehensive Cancer Center.

Conclusion: Key Take-Away Points and Final Thoughts

July 16th 2013

Therapies in Development for Medullary Thyroid Cancer

July 16th 2013

Treatment-Related Toxicity in Advanced MTC

July 16th 2013

Mutations and Targeted Therapies in Advanced MTC

July 16th 2013

Treating Advanced Medullary Thyroid Cancer

July 16th 2013

Multidisciplinary Treatment of Medullary Thyroid Cancer

July 16th 2013

Nonsurgical Treatment Options for Early-Stage MTC

July 16th 2013

Staging of Patients With Medullary Thyroid Cancer

July 16th 2013

Genetic Testing and Screening in Advanced MTC

July 16th 2013

Genetic Testing and Screening in Medullary Thyroid Cancer

July 16th 2013

Customizing Imaging Based on Calcitonin Levels in MTC

July 16th 2013

Introduction and Overview of MTC Diagnosis Challenges

July 16th 2013

Dr. Swain Discusses Studies From the 2013 ASCO Meeting

July 15th 2013

Sandra Swain, MD, medical director of the Washington Cancer Institute at MedStar Washington Hospital Center, highlights information presented at the 2013 American Society of Clinical Oncology (ASCO) Meeting.

NCI Develops Large Dataset of Genomic Variants Across Nine Common Cancer Types

July 15th 2013

Researchers at the National Cancer Institute have developed a comprehensive analysis of coding variants in nine of the most frequently studied human tumor cell lines in cancer research.

FDA Approves Afatinib for Metastatic NSCLC

July 12th 2013

The FDA has approved afatinib, along with a companion diagnostic, to treat patients with metastatic non-small cell lung cancer who express specific types of EGFR mutations.

Dr. Tabernero on Molecular Characterization in GI Cancer

July 12th 2013

Josep Tabernero, MD, PhD, from the Vall d'Hebron University Hospital, believes that in order to treat patients with gastrointestinal cancers more effectively, researchers must focus on the molecular classification of particular subpopulations.

Research Spotlight: Promising Phase I Results

July 12th 2013

Highlights of key findings from several phase I clinical trials that provide insight into new and emerging druggable targets and targeted therapies.