Gastrointestinal Cancer | Specialty

The OncLive Gastrointestinal Cancer condition center page is a comprehensive resource for clinical news and expert insights on various types of gastrointestinal (GI) cancers, including hepatocellular carcinoma, gastric cancer, pancreatic cancer, colorectal cancer, cholangiocarcinoma, esophageal cancer, and more. This page features news articles, interviews in written and video format, and podcasts that focus on unmet needs, treatment advances, and ongoing research in GI cancers.

Trastuzumab Deruxtecan Active in HER2-Expressing Gastric Cancer

January 19th 2018

The novel investigational HER2-targeting antibody-drug conjugate trastuzumab deruxtecan showed promising antitumor activity in heavily pretreated patients with HER2-expressing gastric cancer.

Classifying NETs Versus NECs in Gastrointestinal Cancer

January 18th 2018

Jennifer Eads, MD, discusses the classification of NETs versus NECs in gastrointestinal cancer.

Dr. O'Reilly on Areas of Research in Pancreatic Cancer

January 18th 2018

Eileen O’Reilly, MD, associate director for clinical research at Memorial Sloan Kettering Cancer Center discusses areas of research for patients with pancreatic cancer.

Pancreatic Ductal Carcinoma: Slow Progress for a Hard-to-Treat Cancer

January 17th 2018

Pancreatic ductal adenocarcinoma, which is considered incurable, accounts for more than 90% of pancreatic cancer cases.

Cabozantinib Improves OS, PFS in Advanced HCC

January 17th 2018

Treatment with cabozantinib improved median overall survival by 2.2 months compared with placebo for patients with previously treated advanced hepatocellular carcinoma.

Dr. Saltz Discusses FOLFIRINOX in Colorectal Cancer

January 17th 2018

Leonard Saltz, MD, executive director for Clinical Value & Sustainability, head, Colorectal Oncology Section, Memorial Sloan Kettering Cancer Center, discusses the option of FOLFIRINOX for the treatment of patients with metastatic colorectal cancer.

Dr. Abou-Alfa Discusses Treatment Options in Liver Cancer

January 17th 2018

Ghassan K. Abou-Alfa, MD, medical oncologist, Memorial Sloan Kettering Cancer Center, discusses treatment options in liver cancer.

No Reduction in HRQOL With Neoadjuvant Chemoradiotherapy in Esophageal Cancer

January 15th 2018

Neoadjuvant chemoradiotherapy did not lower postoperative health-related quality of life compared with surgery alone for patients with esophageal or junctional cancer.

Dr. Janjigian on Conducting MSI Testing in Gastric Cancer

January 13th 2018

Yelena Y. Janjigian, MD, medical oncologist, Memorial Sloan Kettering Cancer Center, discusses when to conduct microsatellite instability (MSI) testing for patients with gastric cancer.

FGFR Inhibitor Tested in Hard-to-Treat GI Cancer

January 13th 2018

Given that few options are available for intrahepatic cholangiocarcinoma, investigators are excited about a phase III trial of the multikinase inhibitor derazantinib as a second-line treatment for patients with inoperable or advanced disease.

Dr. Eads Discusses the Classification of Gastrointestinal NETs

January 12th 2018

Jennifer Eads, MD, assistant professor, senior clinical instructor, department of medicine, University Hospitals Cleveland Medical Center, discusses the classification of gastrointestinal neuroendocrine tumors.

TAS-102 Improves Survival in Asian mCRC Patients

January 12th 2018

TAS-102 improved overall survival compared with placebo in previously treated Asian patients with metastatic colorectal cancer (mCRC).

Efforts Continue to Optimize Immunotherapy in Gastric Cancer

January 10th 2018

David H. Ilson, MD, PhD, discusses practice-changing trials, the optimal available therapies, and how immunotherapy fits into the future treatment paradigm for gastric cancer.

Marshall Recaps Milestones in CRC Paradigm

January 10th 2018

John L. Marshall, MD, recaps some of the biggest CRC advancements of 2017, and explains what those successes mean for the treatment paradigm moving forward.

Understanding the Implications of Mutational Status in Intrahepatic Cholangiocarcinoma

January 9th 2018

Jesper B. Andersen, MSc, PhD, discusses the findings of a study evaluating a single-gene dissection approach in patients with intrahepatic cholangiocarcinoma.

Novel Technology Emerging in GI Cancer Treatment Landscape

January 9th 2018

Christopher Crane, MD, discusses modern innovative techniques in GI cancers.

Novel Approaches May Push Pancreatic Cancer Treatment Forward

January 9th 2018

Eileen O’Reilly, MD, discusses novel therapeutic approaches for the treatment of patients with pancreatic cancer.

Dr. O'Reilly on Immunotherapy in Pancreatic Cancer

January 8th 2018

Eileen O'Reilly, MD, associate director for clinical research at Memorial Sloan Kettering Cancer Center, discusses the role of immunotherapy in patients with pancreatic cancer.

Liver-Directed Therapy Shows Improvement in mCRC

January 5th 2018

Nancy E. Kemeny, MD, discusses the combination of pump and systemic therapy as a liver-directed treatment option for patients with metastatic colorectal cancer.

Developments With Gastrointestinal NETs Continue to Grow

January 5th 2018

Diane Reidy-Lagunes, MD, discusses ongoing developments for the treatment of patients with gastrointestinal and pancreatic NETs.