Gastrointestinal Cancer | Specialty

The OncLive Gastrointestinal Cancer condition center page is a comprehensive resource for clinical news and expert insights on various types of gastrointestinal (GI) cancers, including hepatocellular carcinoma, gastric cancer, pancreatic cancer, colorectal cancer, cholangiocarcinoma, esophageal cancer, and more. This page features news articles, interviews in written and video format, and podcasts that focus on unmet needs, treatment advances, and ongoing research in GI cancers.

Expanded Use of Gleevec Approved in Patients With GIST

February 1st 2012

The FDA granted regular approval for imatinib for treating patients after the surgical removal of KIT-positive GISTs.

Lower Rate of Colorectal Cancer Screening May Be Linked to Higher Cancer Fatalism

January 19th 2012

Higher cancer fatalism, a term that refers to the belief that a cancer diagnosis leads inevitably to death, may be associated with a lower rate of colorectal cancer screening.

Men With Colorectal Cancer Often Not Consulted About Risks for Erectile Dysfunction

January 17th 2012

Men with colorectal cancer are not routinely informed about the potential for erectile dysfunction or how the condition can best be managed.

Prediagnosis Primary Care Visits Improve Outcomes in Medicare Patients With Colorectal Cancer

January 16th 2012

Medicare beneficiaries with CRC who made a higher number of visits to their PCP before their diagnosis had lower disease-related mortality and lower all-cause mortality.

Dr. Chan Discusses the VEGF-Trap Agent Aflibercept

January 13th 2012

Dr. Emily Chan, from Vanderbilt-Ingram Cancer Center, Discusses the VEGF-Trap Agent Aflibercept

Colorectal Tumor Marker: Molecular Evaluation Sheds Light on Negative Lymph Node Status

December 5th 2011

The presence or absence of lymph node involvement has long been recognized as a critically relevant prognostic factor in solid tumor oncology.

Dr. Chan on the Adjuvant Colorectal NO147 Trial

November 30th 2011

Dr. Emily Chan from Vanderbilt-Ingram Cancer Center Discusses the Adjuvant Colorectal NO147 Trial

Dr. Grothey Discusses Novel Agents for Colorectal Cancer

November 11th 2011

Dr. Axel Grothey from the Mayo Clinic Discusses Novel Agents for Colorectal Cancer

Colorectal Cancer: A Review

November 10th 2011

Colorectal cancer is the third most common type of cancer diagnosed in the United States and is the third most common cause of cancer-related death.

Prudent Diet May Help Prevent Colorectal Adenomas in Black Women

November 8th 2011

Investigators are recommending that black women follow a 'prudent dietary pattern' in lieu of a more Western-style diet to prevent the development of colorectal adenomas.

Dr. Grothey on Trastuzumab for Gastroesophageal Cancer

November 7th 2011

Dr. Axel Grothey from the Mayo Clinic on Trastuzumab for Gastroesophageal Cancer

High Folate Intake May Cut Colorectal Cancer Risk

November 1st 2011

New results suggest that a high intake of both natural and synthetic folate is associated with a decreased likelihood of colorectal cancer.

Progress Made, but More Work Lies Ahead in CLL and CRC Treatment

October 31st 2011

A look at the benefits of the chemoimmunotherapy rituximab for CLL and a look at the treatments and advances made in treating metastatic CRC.

Metastatic Colorectal Cancer Study Demonstrates Improved Overall Survival

October 26th 2011

A late phase metastatic colorectal cancer trial was stopped after demonstrating a statistically significant improvement in OS.

Aflibercept Improves Survival in Metastatic Colorectal Cancer Patients

September 26th 2011

Aflibercept added to FOLFIRI chemotherapy improved PFS and OS in previously treated patients with metastatic colorectal cancer.

Noninvasive Stool Test Effectively Detects Colon Cancer

September 19th 2011

The iFOBT test examines the stool for hidden blood, which could come from anywhere in the GI tract, and possibly indicates a colon tumor or precancerous growths known as polyps.

Number of Lymph Nodes Examined for Colon Cancer Increases but Proportion of Node-Positive Cancers Does Not

September 14th 2011

A greater number of lymph nodes are being screened in colon cancer but this has not led to more diagnoses of node-positive colon cancer.

ASCO Highlights: Trials in Progress

August 23rd 2011

The following is a roundup of TPS abstracts that feature trials open to patients aged >17 years with a broad range of cancer types.

3 New Genetic Mutations Establish Hereditary Link in Esophageal Cancer

July 27th 2011

Three new genetic mutations have been identified in patients with Barrett's esophagus (BE) and esophageal adenocarcinoma (EAC).

Jury Still Out on Oxaliplatin for Early-Stage Colon, Rectal Cancers

July 26th 2011

Adding oxaliplatin to 5-fluorouracil before and after surgery for the treatment of locally advanced rectal cancer is demonstrating significant benefit.