Hematologic Oncology | Specialty

The OncLive Hematology Oncology condition center page is a comprehensive resource for clinical news and expert insights on various hematologic malignancies, including leukemias, lymphomas, myeloproliferative neoplasms, multiple myeloma, and much more. This section features news articles, interviews in written and video format, and podcasts that focus on unmet needs, treatment advances, and ongoing research in hematologic cancers.

Bispecific CD19/CD22 CAR T Cells Active in Pediatric Relapsed ALL

April 28th 2020

Treatment with CD19/22 chimeric antigen receptor CAR T cells induced a promising response in patients with relapsed/refractory B-cell precursor acute lymphoblastic leukemia.

Vecabrutinib Shows Evidence of Stable Disease in High-Risk B-Cell Malignancies

April 28th 2020

John N. Allan, MD, discusses the study results of a phase 1b/2 dose-escalation trial with vecabrutinib in patients with B-cell malignancies.

Dr. Thirman on the Rationale for Using SNDX-5613 in Acute Leukemias

April 28th 2020

Michael J. Thirman, MD, discusses the clinical rationale for using the investigational agent SNDX-5613 to treat a subtype of acute myeloid leukemia and acute lymphoblastic leukemia.

Dr. Rizvi on the Limitations of ABVD in Hodgkin Lymphoma

April 24th 2020

Syed Rizvi, MD, discusses the limitations of doxorubicin, bleomycin, vinblastine, and dacarbazine in Hodgkin lymphoma.

Dr. Grossbard on the Activity of Venetoclax in Follicular Lymphoma

April 24th 2020

Michael L. Grossbard, MD, discusses the activity of venetoclax in follicular lymphoma.

Dr. Altomare on the Challenges of Treating ITP

April 24th 2020

Ivy P. Altomare, MD, discusses some of the challenges of treating patients with immune thrombocytopenia.

Brentuximab Vedotin Plus Nivolumab Impresses in Older Patients With Hodgkin Lymphoma

April 24th 2020

Christopher A. Yasenchak, MD, discusses findings from the phase 2 trial with brentuximab vedotin and nivolumab in patients with newly diagnosed classical Hodgkin lymphoma.

Screening Is Critical Component of TA-TMA Management

April 23rd 2020

Christopher E. Dandoy, MD, MSc, discusses the clinical features of TA-TMA and the importance of close monitoring and intervention for patients at risk of developing the disorder.

Pembrolizumab FDA Applications Resubmitted for Updated Dosing Schedule

April 23rd 2020

Supplemental biologics license applications have been resubmitted to the FDA for pembrolizumab to include an every-6-weeks option at 400 mg over 30-minute infusions across multiple indications.

Ruxolitinib REACH2 aGVHD Data Show Superiority Over Standard Care

April 23rd 2020

The REACH2 ruxolitinib acute graft-versus-host disease data have been published in the New England Journal of Medicine.

Dr. Feldman on the Utility of PET Scan in Hodgkin Lymphoma

April 23rd 2020

Tatyana Feldman, MD, discusses the utility of PET Scan in Hodgkin Lymphoma.

Dr. Bannerji on Ongoing Research With REGN1979 in Non-Hodgkin Lymphoma

April 23rd 2020

Rajat Bannerji, MD, PhD, hematologist/oncologist and chief of hematologic malignancies at the Rutgers Cancer Institute of New Jersey, discusses ongoing research with the bispecific antibody REGN1979 in non-Hodgkin lymphoma (NHL).

Expert Highlights Novel Agents in Acute GVHD

April 23rd 2020

Mark A. Schroeder, MD, discusses emerging therapeutic strategies for patients with acute GVHD.

FDA Grants RMAT Designation to Tisagenlecleucel for Follicular Lymphoma

April 22nd 2020

The FDA has granted a Regenerative Medicine Advanced Therapy designation to tisagenlecleucel for the treatment of patients with relapsed/refractory follicular lymphoma.

Dr. Brody on the Role of Immunotherapy in Indolent Lymphomas

April 22nd 2020

Joshua Brody, MD, discusses the role of immunotherapy in indolent lymphomas.

Dr. Davies on Research Efforts in Lenalidomide-Refractory Myeloma

April 21st 2020

Faith E. Davies, MD, discusses the research being done in patients with multiple myeloma who are refractory to lenalidomide.

Bispecific Antibody Is Highly Active in Relapsed/Refractory Non-Hodgkin Lymphoma

April 20th 2020

Rajat Bannerji, MD, PhD, discusses the clinical activity of the bispecific antibody REGN1979 in patients with non-Hodgkin lymphoma.

Dr. Kansagra on Updates With CAR T-cell Therapy in Myeloma

April 18th 2020

Ankit Kansagra, MD, discusses updates with CAR T-cell therapy in multiple myeloma.

Dr. Anderson on the GRIFFIN Study With D-RVd in Multiple Myeloma

April 18th 2020

Larry Anderson, MD, PhD, discusses the phase II GRIFFIN trial examining the addition of daratumumab (Darzalex) to lenalidomide (Revlimid), bortezomib (Velcade), and dexamethasone (D-RVd) in patients with multiple myeloma.

Dr. Nagalla on the Utility of DOACs in Cancer-Associated Thrombosis

April 18th 2020

Srikanth Nagalla, MD, discusses the utility of direct oral anticoagulants in cancer-associated thrombosis.