Lung Cancer | Specialty

The OncLive Lung Cancer condition center page is a comprehensive resource for clinical news and expert insights on non–small cell lung cancer, small cell lung cancer, mesothelioma, and more. This page features news articles, interviews in written and video format, and podcasts that focus on unmet needs, treatment advances, and ongoing research in lung cancer.

Therapy of Non-Small Cell Lung Cancer: Past, Present, and Future

April 9th 2012

New and relevant studies are examining the role of histology, biomarkers, and growth factor receptor inhibitors in the treatment of NSCLC.

Support for LDCT Screenings of Heavy Smokers Is Growing

April 4th 2012

The concept of screening people at high risk for developing lung cancer with low-dose computed tomography continues to gain support in the oncology community.

Examining Crizotinib's Potential Uses

March 29th 2012

The development of crizotinib has helped crystallize a relatively rare molecular subset of NSCLC and holds the potential for wider use in treating patients with the disease.

Preoperative Chemotherapy Shows Promise in Early Lung Cancer

March 28th 2012

Preoperative gemcitabine plus cisplatin followed by radical surgery is feasible, tolerable, and active in patients with early-stage non-small cell lung cancer.

Dr. Gore on Hypofractionated Radiation Therapy

March 22nd 2012

Dr. Elizabeth Gore, from the Medical College of Wisconsin, Discusses Hypofractionated Radiotherapy

Five Questions for Jill M. Siegfried, PhD

March 22nd 2012

Jill M. Siegfried, PhD, is an investigator into the role of growth factors and hormones in the development and growth of lung cancer.

Pursuing an Ethic of Service: Lung Cancer Researcher Noted for Drug Discovery, Charitable Works

March 13th 2012

An interview with Mark G. Kris, MD, chief of the Thoracic Oncology Service at Memorial Sloan-Kettering Cancer Center, who has dedicated the past 30 years to helping patients with lung cancer.

Dr. Perez-Soler on the Future of Lung Cancer Therapies

March 13th 2012

Dr. Roman Perez-Soler, from Albert Einstein College of Medicine, on the Future of Lung Cancer Therapies

Dr. Belani Discusses Driver Mutations in NSCLC

March 7th 2012

Dr. Chandra Belani from Penn State Hershey Cancer Institute Discusses Driver Mutations in NSCLC

Dr. Perez-Soler on Treatment Options for NSCLC

February 14th 2012

Dr. Roman Perez-Soler, from Montefiore Medical Center, on Treatment Options for NSCLC

Radiation Therapy After Surgery Shows No Survival Benefit for Elderly Lung Cancer Patients

February 13th 2012

Many older patients with stage III lung cancer who received radiation therapy fared no better than those who did not receive radiation therapy.

Changing Paradigms for NSCLC in Personalized Therapy Era

January 20th 2012

With the discovery of mutation drivers for NSCLC--including EGFR, KRAS, and EMLA 4-ALK--targeted therapies directed to those mutations are beginning to make a difference.

Continuing Chemotherapy to Near Death Offers No Benefits in Older Patients With Advanced Lung Cancer

January 19th 2012

An aggressive approach to care involving the continuation of chemotherapy within 2 weeks of death does not improve survival in elderly patients with metastatic NSCLC.

SCLC on the Wane, but Difficult to Treat

January 18th 2012

Patients with limited and extensive SCLC show incremental gains with different treatment strategies but so far novel agents have failed to make a difference in outcomes.

No Survival Advantage for High-Dose Radiation Versus Standard-Dose Radiation in Stage III NSCLC

January 11th 2012

High-dose radiation was no better than standard-dose radiation given concurrently with chemotherapy in extending survival of patients with advanced unresectable NSCLC.

Patients With Lung Cancer Often Receive Excess Radiation

January 4th 2012

Patients undergoing lung resection for NSCLC are frequently exposed to a higher dose of radiation than that which has been deemed safe for healthcare workers.

Dr. Belani Discusses NSCLC Adjuvant Therapy

January 3rd 2012

Dr. Chandra Belani, from the Penn State Hershey Cancer Institute, Discusses NSCLC Adjuvant Therapy

Biomarker Identifies Patients With Advanced Lung Cancer Who Will Gain Most From Add-On Cetuximab

December 22nd 2011

Investigators reported that high tumor EGFR expression is a predictive biomarker that defines patients with advanced NSCLC who are most likely to derive a survival benefit from the addition of cetuximab to platinum-based, first-line chemotherapy.

Hospitals for Vulnerable Patients Less Likely to Provide Optimal Lung Cancer Care

December 19th 2011

New data show that patients treated for lung cancer at high safety-net burden hospitals undergo curative-intent surgery significantly less often than individuals treated at low safety-net burden facilities.

5 Questions for Martin Steffen, MD, PhD

December 15th 2011

Martin Steffen, MD, PhD, developed phosphorylation signatures that discriminate between lung tumors and normal lung, and is developing signatures for the prediction of therapy response.