Lung Cancer | Specialty

The OncLive Lung Cancer condition center page is a comprehensive resource for clinical news and expert insights on non–small cell lung cancer, small cell lung cancer, mesothelioma, and more. This page features news articles, interviews in written and video format, and podcasts that focus on unmet needs, treatment advances, and ongoing research in lung cancer.

Checkpoint Inhibitors, Electrical Fields Provide New Options for Mesothelioma

August 31st 2021

Despite an outsized reputation fueled by late-night commercials from personal injury lawyers, mesothelioma is a rare disease with approximately 3000 new diagnoses every year in the United States.

Addition of Veliparib to Frontline Chemo Misses OS End Point in Current Smokers With Advanced Squamous NSCLC

August 31st 2021

The addition of veliparib to platinum-based chemotherapy in the frontline treatment of current smokers with advanced squamous non–small cell lung cancer did not significantly improve overall survival, but the LP52 signature may identify a subset of patients who will derive benefit from the combination.

Nivolumab and Tumor-Infiltrating Lymphocyte Regimen Elicits Activity in Metastatic NSCLC

August 27th 2021

Nivolumab followed by tumor-infiltrating lymphocyte therapy and maintenance nivolumab demonstrated a suitable safety profile and antitumor activity in patients with metastatic non–small cell lung cancer.

Dr. Patil on Key Developments With Targeted Therapy in Lung Cancer

August 26th 2021

Pradnya D. Patil, MD, FACP, discusses recent developments with targeted therapies in lung cancer.

Dr. Chu on Ongoing Efforts to Address Disparities in Lung Cancer

August 26th 2021

Edward Chu, MD, MMS, discusses ongoing efforts to address disparities in lung cancer at Montefiore and Albert Einstein College of Medicine.

NSCLC: Final Thoughts

August 26th 2021

The discussion about the evolution of precision medicine in non–small cell lung cancer (NSCLC) ends as each expert discusses their final thoughts.

Future Directions in Treatment of Small Cell Lung Cancer

August 26th 2021

Panelists conclude their discussion by commenting on areas of unmet need and sharing personal perspectives on factors that may change clinical practice for SCLC in the future.

Emerging Treatments in SCLC: Impact of Targeted Therapy

August 26th 2021

Key opinion leaders in lung cancer share personal thoughts on the potential for bispecific agents and the overall impact of inhibiting molecular targets.

NSCLC: Overcoming Challenges

August 26th 2021

Oncology experts provide insight on screening methods available and discuss strategies that may address challenges in identification of targetable mutations/tumor profiles in non–small cell lung cancer (NSCLC).

Dr. Goldman on Key Takeaways From the CASPIAN Trial in Frontline ES-SCLC

August 25th 2021

Jonathan W. Goldman, MD, discusses key takeaways from the phase 3 CASPIAN trial in patients with extensive-stage small cell lung cancer.

Dr. Dietrich on Navigating the NSCLC Treatment Landscape

August 25th 2021

Martin Dietrich, MD, PhD, shares how he navigates the non–small cell lung cancer (NSCLC) treatment landscape.

Immunotherapy for NSCLC: Clinical Pearls

August 25th 2021

Final takeaways from ASCO 2021 and the use of immunotherapy to treat various types of patients with non–small cell lung cancer.

Blood-Based Biomarkers in NSCLC

August 25th 2021

The potential clinical utility of blood-based biomarkers in non–small cell lung cancer based on recent data presented at ASCO 2021.

Perioperative Approaches to NSCLC

August 25th 2021

Drs Chaitali Nangia and Sandip P. Patel debate between best treatment approaches for patients with non–small cell lung cancer in the perioperative setting.

Dr. Pecot on Addressing Mechanisms of Resistance With New Targeted Therapies in NSCLC

August 24th 2021

Chad V. Pecot, MD, discusses addressing mechanisms of resistance with new targeted therapies in non–small cell lung cancer.

Dr. Stevenson on Ongoing Research Efforts in ES-SCLC

August 23rd 2021

James Stevenson, MD, discusses ongoing research efforts that are generating excitement in extensive-stage small cell lung cancer.

CT-Based Image Guidance Identifies COVID-19 in Radiotherapy Treated–Lung Cancer

August 20th 2021

Computed tomography-based image guidance during radiation therapy could be a method of identifying patients who require a complete workup for COVID-19.

Dr. Spicer on Outcomes from the CheckMate-816 Trial in NSCLC

August 20th 2021

Jonathan Spicer, MD, PhD, discusses the efficacy observed with neoadjuvant nivolumab plus platinum-doublet chemotherapy in patients with resectable non–small cell lung cancer.

Toripalimab Plus Chemo Meets PFS End Point in Frontline Advanced NSCLC

August 19th 2021

The addition of toripalimab to chemotherapy resulted in a significant improvement in progression-free survival compared with chemotherapy alone when given as first-line treatment in patients with non–small cell lung cancer, meeting the primary end point of the phase 3 CHOICE-01 trial.

Nivolumab Followed by TIL Therapy Shows Early Safety, Clinical Activity in Metastatic NSCLC

August 19th 2021

Nivolumab followed by treatment with tumor-infiltrating lymphocytes was generally safe and found to have clinical benefit in patients with metastatic non–small cell lung cancer.