Non-Hodgkin Lymphoma | Specialty

Final GENUINE Data Support Addition of Ublituximab to BTK Inhibitors in Relapsed/Refractory, High-Risk CLL

February 23rd 2021

Feburary 23, 2021 — The addition of the anti-CD20 monoclonal antibody ublituximab to ibrutinib led to a statistically higher overall response rate over ibrutinib alone with acceptable safety in patients with relapsed/refractory, high-risk, chronic lymphocytic leukemia.

R/R Follicular Lymphoma: Second-line Treatment Selection

February 22nd 2021

Factors that hematologist-oncologists need to consider when selecting second-line therapy for relapsed follicular lymphoma.

R/R Follicular Lymphoma: Patient Prognosis

February 22nd 2021

Insight regarding the prognosis for patients with follicular lymphoma who relapse and impact of treatment sequencing on this trajectory.

CAR T-Cell Therapy for R/R DLBCL

February 19th 2021

Novel Therapies for R/R DLBCL

February 19th 2021

Giants of Cancer Care Honorees June and Rosenberg Receive Prestigious Prize

February 17th 2021

February 17, 2021 - Carl H. June, MD, and Steven A. Rosenberg, MD, PhD, have received the 2021 Dan David Prize Laureate for their research in oncology. They, along with Zelig Eshhar, an immunologist at the Weizmann Institute of Science and the Tel Aviv Sourasky Medical Center, will share a prize of $1 million.

FDA Accepts Application for Zanubrutinib in Waldenström Macroglobulinemia

February 17th 2021

February 17, 2021 — The FDA has accepted a supplemental new drug application of zanubrutinib for the treatment of adult patients with Waldenström macroglobulinemia.

Off-the-Shelf NK Immunotherapy With Chemotherapy and Transplant Shows Early Activity in B-Cell NHL

February 17th 2021

February 17, 2021 — Cord blood–derived natural killer immunotherapy, when paired with high-dose chemotherapy and autologous stem cell transplant, showcased early antitumor activity in patients with B-cell non-Hodgkin lymphoma.

Treatment Options in Relapsed/Refractory Chronic Lymphocytic Leukemia

February 17th 2021

Experts discuss second-line treatment options in relapsed/refractory chronic lymphocytic leukemia, including a discussion on the MURANO trial.

Chronic Lymphocytic Leukemia Treatment Considerations 

February 17th 2021

Dr Brown and Dr Stilgenbauer provide advice for community-based oncologists treating chronic lymphocytic leukemia.

Targeted Therapies Reign in the Frontline Treatment of CLL

February 16th 2021

Jacqueline Claudia Barrientos, MD, MS, explaines how she navigates among the options available in the frontline setting for patients with CLL and highlighted ongoing research efforts of interest.

Braunschweig Makes the Case for Earlier Use of CAR T-Cell Therapy in DLBCL

February 16th 2021

CAR T-cell therapy has shown robust responses and curative potential in patients with diffuse large B-cell lymphoma, regardless of cytogenetics or age.

Epperla Elucidates on Excitement With Tafasitamab and Selinexor in DLBCL

February 15th 2021

Narendranath Epperla, MD, MS, expands on findings from the L-MIND trial in DLBCL, as well as the significance of selinexor and other options in the pipeline.

R/R DLBCL: Treating With Tafasitamab-Lenalidomide

February 12th 2021

Tafasitamab Combined With Lenalidomide in R/R DLBCL

February 12th 2021

Role of Venetoclax in Chronic Lymphocytic Leukemia

February 10th 2021

Experts comment on the use of venetoclax-based therapy in treating chronic lymphocytic leukemia.

A Look at the ECOG 1912 and iLLUMINATE Trials

February 10th 2021

Experts Dr Stilgenbauer and Dr Ghia highlight and comment on the ECOG 1912 and iLLUMINATE trials.

Dr. Ahmed on Axi-Cel Benefit in Patients With Primary Refractory LBCL

February 9th 2021

Sairah Ahmed, MD, discusses the efficacy of axicabtagene ciloleucel (axi-cel; Yescarta) in patients with refractory large B-cell lymphoma (LBCL) who achieved complete remission (CR) to any prior treatment versus those who were primary refractory.

Response to Prior Therapy Predicts Outcomes With Axi-Cel in Refractory Large B-Cell Lymphoma

February 9th 2021

February 9, 2021 - Patients with refractory large B-cell lymphoma have less to gain from axicabtagene ciloleucel if they have never achieved a complete response to any line of prior therapy.

Liso-Cel Responses Not Impacted By Prior Anti-CD19 Therapy in Relapsed/Refractory Large B-Cell Lymphoma

February 8th 2021

February 8, 2021 - Prior exposure to anti-CD19 therapy did not impact response to the CAR T-cell therapy lisocabtagene maraleucel in patients with relapsed/refractory large B-cell lymphoma.