Non-Hodgkin Lymphoma | Specialty

Expert Discusses JCAR017 CAR T-Cell Therapy in Non-Hodgkin Lymphoma

March 6th 2017

Leo I. Gordon MD, discusses results from the TRANSCEND trial and the next steps with chimeric antigen receptor T-cell therapy in non-Hodgkin lymphoma.

Juno Accelerates Development of JCAR017, Halts JCAR015

March 2nd 2017

Juno therapeutics has shifted its focus toward the development of JCAR017 for relapsed/refractory diffuse large B-cell lymphoma after a series of toxicity-related setbacks culminated in the need to halt the development of JCAR015.

Ibrutinib Benefit in Waldenstrom Macroglobulinemia Sustained With Latest Data

March 2nd 2017

Single-agent ibrutinib induced a response rate of 90% at a median follow-up of 18.1 months in rituximab-refractory patients with Waldenstrom macroglobulinemia, according to results from an open-label substudy of the ongoing phase III iNNOVATE trial published in The Lancet Oncology.

Dr. Salles on Frontline Management of Follicular Lymphoma

March 1st 2017

Gilles Salles, MD, PhD, Centre Hospitalier Lyon-Sud, discusses frontline treatment management for patients with follicular lymphoma.

Dr. Fowler on FLIPI Scoring System in Follicular Lymphoma

March 1st 2017

Nathan Fowler, MD, associate professor, The University of Texas MD Anderson Cancer Center, discusses the FLIPI scoring system in follicular lymphoma.

Axicabtagene Ciloleucel Shows High CR Rates in Primary Analysis of ZUMA-1 Study

February 28th 2017

Treatment with axicabtagene ciloleucel demonstrated an objective response rate of 82% and a complete response rate of 54% for patients with aggressive non-Hodgkin lymphoma.

Axicabtagene Ciloleucel Shows Response Rate of 76% in Aggressive Lymphoma

February 27th 2017

Axicabtagene ciloleucel had an objective response rate of 76% and a complete response rate of 47% in patients with aggressive non-Hodgkin lymphoma followed for at least 1 month.

Researchers Examine Acquired Mutations Linked to Ibrutinib Resistance in CLL

February 25th 2017

Researchers hope the acquired ibrutinib resistance mutations BTK and PLCG2 can be used as biomarkers for early intervention opportunities in patients with chronic lymphocytic leukemia.

Dr. Salles on Improving Immune Respone in Follicular Lymphoma

February 15th 2017

Gilles A. Salles, MD, PhD, Centre Hospitalier Lyon-Sud, discusses improving immune response in follicular lymphoma.

Dr. Reeder on Future Treatment Approaches in Aggressive Lymphomas

February 8th 2017

Craig B. Reeder, MD, assistant professor of Medicine, Mayo Clinic, discusses some future treatment approaches for patients with aggressive lymphomas, including diffuse large B-cell lymphoma.

Upfront Ibrutinib Continues to Impress in CLL

February 3rd 2017

At 29 months’ follow-up, frontline ibrutinib reduced the risk of of progression or death by 88% versus chlorambucil in patients with chronic lymphocytic leukemia or small lymphocytic lymphoma, according to the latest findings from the phase III RESONATE-2 trial.

Dr. Beaupre on Ibrutinib in Marginal Zone Lymphoma

February 2nd 2017

Darrin M. Beaupre, MD, head of Early Development and Immunotherapy at Pharmacyclics, discusses a trial exploring the efficacy of ibrutinib in patients with marginal zone lymphoma.

Dr. Rosenthal on FDA Approval of Ibrutinib in Marginal Zone Lymphoma

January 20th 2017

Allison C. Rosenthal, DO, hematology consultant, Mayo Clinic, discusses the FDA approval of of ibrutinib (Imbruvica) as a treatment for patients with marginal zone lymphoma (MZL).

FDA Approves Ibrutinib for Marginal Zone Lymphoma

January 19th 2017

The FDA has granted an accelerated approval to ibrutinib as a treatment for patients who require systemic therapy with marginal zone lymphoma following at least one prior anti-CD20-based therapy, based on findings from a single-arm phase II study.

Frontline Ibrutinib Benefit Sustained in Pivotal CLL Trial Update

January 17th 2017

Danelle James, MD, discusses the updated RESONATE-2 data presented at the ASH Annual Meeting and the next steps with ibrutinib in CLL.

Younes Discusses Key ASH Data in MCL, DLBCL

January 13th 2017

The fields of mantle cell lymphoma and diffuse large B-cell lymphoma had a handful of updates presented during the 2016 ASH Annual Meeting.

The Future of Treatment of B-Cell Lymphoma

January 13th 2017

DLBCL: CAR-T as Curative Treatment/Bridge to Transplant

January 13th 2017

CAR-T Therapy for DLBCL

January 13th 2017

Relapsed/Refractory DLBCL

January 13th 2017