Pediatric Oncology | Specialty

The OncLive Pediatric Oncology condition center page is a comprehensive resource for clinical news and expert insights on various types of cancers in pediatric patients, including acute lymphoblastic leukemia, acute myeloid leukemia, brain cancers, sarcomas, and more. This page features news articles, interviews in written and video format, and podcasts that focus on unmet needs, treatment advances, and ongoing research in childhood and adolescent and young adult cancers.

Dr. Upadhyaya on the Design of the SJYC07 Trial in Pediatric Patients With Ependymoma

October 4th 2018

Santhosh Upadhyaya, MD, neuro-oncologist, St. Jude Children’s Research Hospital, discusses the design of the 10-year-long SJYC07 trial.

Link Lends Insight on Progress, Challenges in Pediatric Cancer

October 3rd 2018

Michael Link, MD, a 2018 Giant of Cancer Care® in Pediatric Oncology, discusses the exciting progress being made for various pediatric tumors.

Dr. Tasian on Challenges in Treating Pediatric Patients With Ph-Like ALL

September 19th 2018

Sarah K. Tasian, MD, an attending physician and assistant professor of pediatrics in the Division of Oncology at Children’s Hospital of Philadelphia, discusses the challenges in treating pediatric patients with Philadelphia chromosome (Ph)-like acute lymphoblastic leukemia (ALL).

Recognizing Predisposition Syndromes Can Impact Pediatric MDS and AML Treatment

September 14th 2018

Early identification of inherited predisposition to forms of myelodysplastic syndrome and acute myeloid leukemia in pediatric patients can assist in treatment decisions and selection for familial stem cell transplant.

Future of AYA ALL Research Should Include Eliminating MRD, Treating High-Risk Patients

September 13th 2018

Following survival improvements in the field of adolescents and young adults with acute lymphoblastic leukemia, researchers must turn their focus to lowering toxicity, and delivering treatment to high-risk subgroups, among others.

Expert Emphasizes Importance of Collaboration for Rare Pediatric Cancers

September 10th 2018

Matthew Ladra, MD, MPH, discusses the treatment of patients with esthesioneuroblastoma, emphasizing the need for collaboration in this rare malignancy.

Study Evaluates Risk of Breast Cancer for Childhood Survivors of Cancer

September 7th 2018

Zhaoming Wang, PhD, discusses the first assessment of the joint effects of rare and common genetic variations in survivors of childhood cancers.

Dr. Bosse on Immunotherapy in Pediatric Cancers

September 6th 2018

Kristopher Bosse, MD, attending physician, Division of Oncology, The Children's Hospital of Philadelphia, discusses the use of immunotherapy in the treatment of pediatric patients with cancer.

FDA Grants Pembrolizumab Priority Review for Merkel Cell Carcinoma

September 4th 2018

The FDA has granted a priority review to a supplemental biologics license application for pembrolizumab for the treatment of pediatric and adult patients with recurrent locally advanced or metastatic Merkel cell carcinoma.

Genomic Era Reaches Pediatric Oncology

September 4th 2018

Technological advancements in molecular tumor profiling are starting to make a difference in pediatric oncology, where the search for new therapies is challenging and frustrating.

A Legacy of Hope for Young Leukemia Patients

September 3rd 2018

Joseph V. Simone, MD, is best known for leading the research efforts that resulted in the first curative combination treatment for certain pediatric patients with acute lymphoid leukemia. Under his leadership, the St. Jude Children’s Research Hospital in Memphis, Tennessee, was designated the first and only National Cancer Institute cancer center dedicated to children. He was honored in the Pediatric Oncology category with a 2017 Giants of Cancer Care® award.

FDA Accepts Application for Dasatinib for Pediatric Ph+ ALL

August 30th 2018

The FDA has accepted a supplemental biologics license application for dasatinib for use in combination with chemotherapy for the treatment of pediatric patients with newly diagnosed Philadelphia chromosome–positive acute lymphoblastic leukemia.

Dr. Wang on Genomic Analysis of Breast Cancer Risk in Pediatric Cancer Survivors

August 29th 2018

Zhaoming Wang, PhD, bioinformatics scientist, Department of Computational Biology, St. Jude Children’s Research Hospital, discusses a genomic analysis of breast cancer risk in pediatric cancer survivors.

Dr. Youngblood on the Process of T-Cell Differentiation in Pediatric Solid Tumors

August 23rd 2018

Benjamin A. Youngblood, PhD, assistant member, Department of Immunology, St. Jude Children’s Research Hospital, discusses the process of T-cell differentiation in pediatric solid tumors.

Dr. Desai on Phase I Study of Entrectinib in Solid Tumors

August 20th 2018

Ami Vijay Desai, MD, assistant professor of Pediatrics, University of Chicago Comer Children's Hospital, discusses the design of a phase I study testing entrectinib in patients with solid tumors.

Dr. Engel on the Future of Eltrombopag in HIV-Related Thrombocytopenia

August 17th 2018

Elissa Engel, MD, pediatric resident, University of South Florida, discusses the future of eltrombopag (Promacta) in HIV-related thrombocytopenia.

Dr. Kaplan on the Treatment of Pediatric Patients With Sarcoma

August 17th 2018

Rosandra N. Kaplan, MD, investigator, Pediatric Oncology Branch, Head, Tumor Microenvironment Section, National Cancer Institute, discusses the treatment of pediatric patients with sarcoma.

Only 40% of Pediatric CNS Cancer Survivors Achieve Full Independence as Adults

August 15th 2018

Sixty percent of adult survivors of pediatric CNS tumors do not achieve full functional and social independence, according to results from a study conducted by researchers at St. Jude Children’s Research Hospital and the University of Tennessee Health Science Center.

Greater Grasp of Pediatric Rhabdoid Tumors Needed to Improve Outcomes

August 14th 2018

James I. Geller, MD, describes the ongoing work in pediatric patients with rare rhabdoid tumors.

Antibody-Drug Conjugate Could Lead to Treatment Advances in Pediatric Neuroblastoma

August 13th 2018

Kristopher R. Bosse, MD, discusses how D3-GPC2-PBD could impact pediatric neuroblastoma.