Sarcomas | Specialty

The OncLive Sarcomas/TGCT condition center page is a comprehensive resource for clinical news and expert insights on tenosynovial giant cell tumor (TGCT), soft tissue sarcoma, gastrointestinal stromal tumor, Ewing sarcoma, and more. This page features news articles, interviews in written and video format, and podcasts that focus on unmet needs, treatment advances, and ongoing research in sarcomas and TGCT.

Dr. Kiran Turaga on Advancements in Classification, Imaging in Sarcoma

October 13th 2016

Kiran Turaga, MD, MPH, surgical oncologist, University of Chicago Cancer Center, discusses advancements in the field of sarcoma.

Unexpected Benefit Observed From Neoadjuvant Therapy in High-Risk Soft Tissue Sarcoma

October 10th 2016

A technically negative trial in high-risk adult soft tissue sarcoma nonetheless produced a significant survival benefit for anthracycline-based neoadjuvant chemotherapy.

Beyond Imatinib: Expert Explores Next Frontier in GIST

October 6th 2016

Lori Rink, PhD, discusses the groundbreaking impact of imatinib (Gleevec) in gastrointestinal stromal tumors, the heterogeneity of the disease and its impact on personalizing treatment, and emerging therapies in the field.

Expert Says Immunotherapy Not the "Magic Bullet" in Sarcoma

September 29th 2016

Katherine Thornton, MD, discusses the potential that immunotherapy agents could have in the field of sarcoma, as well as the role of genomic profiling in understanding the patients who may benefit from select treatments.

Study Suggests Superiority of Functional Imaging in Assessing Sarcoma Outcomes

September 26th 2016

A comparison of anatomic and functional imaging in the assessment of clinical outcomes in patients with Ewing sarcoma has shown that FDG-PET, assessed by PERCIST criteria, was superior in predicting clinical benefits and identifying responses.

Trabectedin, Eribulin Advance Sarcoma Care in Approved Indications and Beyond

September 24th 2016

Katherine Thornton, MD, discusses the use of trabectedin and eribulin both within and outside of their approved indications for soft tissue sarcoma.

CHMP Adopts Positive Opinion for Olaratumab in Soft Tissue Sarcoma

September 16th 2016

The Committee for Medicinal Products for Human Use has recommended approval of the PDGFRα antagonist olaratumab for use in combination with doxorubicin for patients with advanced soft tissue. sarcoma who are not good candidates for radiotherapy or surgery.

Dr. George D. Demetri on the Importance of Collaboration in Sarcoma

August 25th 2016

Dr. Federman on Challenges With Treating AYA Patients With Sarcoma

August 19th 2016

Noah Federman, MD, director, Pediatric Bone and Soft Tissue Sarcoma Program, University of California, Los Angeles, discusses the challenges associated with treating adolescent and young adult (AYA) patients with sarcoma.

Collaborative Effort Fuels Sarcoma Advancements

August 15th 2016

Denise Reinke, MS, NP, discusses the Sarcoma Alliance for Research through Collaboration, as well as the challenges and up-and-coming advancements in sarcoma.

Investigator Highlights Remarkable Responses With Pembrolizumab in Sarcoma

August 12th 2016

Treatment with pembrolizumab (Keytruda) led to a reduction of tumor size in 33% of patients with undifferentiated pleomorphic sarcoma and dedifferentiated liposarcoma.

Dr. Jonathan Trent on Pembrolizumab in Advanced Sarcomas

August 9th 2016

FDA Places Partial Hold on Pivotal Trial of T-Cell Therapy in Sarcoma

August 4th 2016

The FDA has placed a partial clinical hold on a planned pivotal trial examining an investigational T-cell therapy in patients with myxoid round cell liposarcoma.

Soft Tissue Sarcoma: Looking Ahead

July 29th 2016

Olaratumab Efficacy in Soft-Tissue Sarcoma

July 29th 2016

Eribulin Mesylate in Soft Tissue Sarcoma

July 29th 2016

Efficacy and Toxicities with Trabectedin in Sarcomas

July 29th 2016

The Role of Trabectedin in Sarcoma Subtypes

July 29th 2016

Recent Approvals in Soft Tissue Sarcoma

July 29th 2016

Sequencing Decisions in Soft Tissue Sarcoma

July 29th 2016