Advancements and New Treatment Options: Optimizing Care for Patients with Graft-vs-Host Disease

Hana Safah, MD, and Corey Cutler, MD, MPH, review recent data in graft-vs-host disease and provide comprehensive insights on treatment practices.

EP. 1: Overview of Graft-vs-Host Disease (GvHD)

February 28th 2024

Experts on graft-vs-host disease (GvHD) introduce themselves and provide an overview of GvHD, highlighting diagnosis, symptoms, risk stratification, and prevention.

EP. 2: How Does GvHD Typically Present?

February 28th 2024

Hematologist-oncologists Corey Cutler, MD, MPH, and Hana Safah, MD, discuss how graft-vs-host disease presents and the importance of early intervention.

EP. 3: Role of Biomarkers in Graft-vs-Host Disease

March 6th 2024

Corey Cutler, MD, MPH, discusses the role of prognostic markers in graft-vs-host disease and how they can potentially inform treatment selection.

EP. 4: Staging Practices for Chronic Graft-vs-Host Disease

March 6th 2024

Hana Safah, MD, reviews the NIH staging system for graft-vs-host disease and discusses the importance of staging in determining prognosis and informing treatment decisions.

EP. 5: First-Line Therapy for Chronic GvHD

March 13th 2024

Hematologist-oncologists discuss the first-line treatment options for patients with chronic GvHD and the advantages and disadvantages of steroids.

EP. 6: Treating Patients With Steroid-Refractory Chronic GvHD

March 13th 2024

Drs Safah and Cutler discuss treatment practices for patients with steroid-refractory graft-vs-host disease and highlight patients who are steroid dependent.

EP. 7: Approved Therapies for Steroid-Refractory Chronic GvHD

March 20th 2024

Hematologist-oncologists give an overview of the 3 approved treatment options for patients with steroid-refractory chronic GvHD—ruxolitinib, ibrutinib, and belumosudil—and highlight the REACH3 and ROCKstar studies.

EP. 8: Therapies in Development for Chronic GvHD

March 20th 2024

Drs Cutler and Safah look to the future of chronic GvHD treatment and discuss ongoing research, highlighting studies investigating axatilimab and abatacept.

EP. 9: Supportive Care and Medication Access in GvHD

March 27th 2024

Hana Safah, MD, and Corey Cutler, MD, MPH, conclude with clinical insights on addressing medication access and the supportive care needs of patients with GvHD.