Latest Conference Articles

The OncLive® Conference page includes a listing of all conferences covered by OncLive®, including the ASCO, ESMO, SITC, EHA, ASH, and SABCS annual meetings, as well as the Chemotherapy Foundation Symposium and Miami Breast Cancer Conference, among many others. Conference coverage incorporates articles and interviews in written and video format.

Dr. Younes on Atezolizumab, Obinutuzumab, and Bendamustine in Follicular Lymphoma

December 11th 2017, 1:57am

ASH Annual Meeting and Exposition

Anas Younes, MD, Chief of Lymphoma Service, Memorial Sloan Kettering Cancer Center, discusses the interim analysis of a study exploring the safety and efficacy of atezolizumab (Tecentriq) in combination with obinutuzumab (Gazya) and bendamustine in patients with previously untreated follicular lymphoma.

PD-1 Inhibitor Cemiplimab Active in B-Lymphoid Malignancies

December 11th 2017, 1:54am

ASH Annual Meeting and Exposition

Cemiplimab as a monotherapy and in combination with the monoclonal antibody REGN1979 demonstrated clinical activity in patients with B-cell non-Hodgkin lymphoma and Hodgkin lymphoma.

Axi-Cel Responses Sustained With Longer Follow-Up for NHL

December 10th 2017, 10:48pm

ASH Annual Meeting and Exposition

Axi-cel (axicabtagene ciloleucel; Yescarta) maintained a complete remission rate of 40% with a median follow-up of 15.4 months for patients with refractory, aggressive non-Hodgkin lymphoma.

Tisagenlecleucel Continues to Impress in DLBCL

December 10th 2017, 10:21pm

ASH Annual Meeting and Exposition

The CAR T-cell therapy tisagenlecleucel (Kymriah) achieved an overall response rate of 53.1% in adult patients with relapsed/refractory diffuse large B-cell lymphoma.

BCMA-Directed bb2121 Highly Effective for Myeloma

December 10th 2017, 10:14pm

ASH Annual Meeting and Exposition

Treatment with the BCMA-directed CAR T-cell therapy bb2121 induced complete remissions for 56% of patients with relapsed/refractory multiple myeloma.

Frontline Brentuximab Vedotin With AVD Bests ABVD for Advanced HL

December 10th 2017, 10:09pm

ASH Annual Meeting and Exposition

The phase III ECHELON-1 study in Hodgkin lymphoma compared the use of A+AVD with standard chemotherapy of doxorubicin, bleomycin, vinblastine, and dacarbazine.

Alternative Agent Shows Clinical Activity in Patients With Advanced Systemic Mastocytosis

December 10th 2017, 9:41pm

ASH Annual Meeting and Exposition

Treatment using BLU-285 (Avapritinib) induced clinically significant activity in patients with an advanced or aggressive form of systemic mastocytosis, according to data from an ongoing phase I trial.

Ibrutinib/Venetoclax Combo Impresses in Early CLL Data

December 10th 2017, 8:37pm

ASH Annual Meeting and Exposition

The combination of ibrutinib (Imbruvica) and venetoclax (Venclexta) elicited a complete response (CR) or CR with incomplete hematologic recovery rate of 47% for patients with relapsed/refractory chronic lymphocytic leukemia.

Mogamulizumab Significantly Improves PFS in CTCL

December 10th 2017, 8:31pm

ASH Annual Meeting and Exposition

The anti-CCR4 monoclonal antibody mogamulizumab reduced the risk of progression or death by 47% compared with vorinostat (Zolinza) in previously treated patients with cutaneous T-cell lymphoma.

Dr. Rogers Discusses Early Intervention With Ibrutinib in CLL

December 10th 2017, 8:25am

ASH Annual Meeting and Exposition

Kerry Rogers, MD, Assistant Professor, Internal Medicine, Division of Hematology, The Ohio State University Comprehensive Cancer Center, discusses a phase II trial of early intervention with ibrutinib (Imbruvica) in patients with asymptomatic, high-risk chronic lymphocytic leukemia (CLL) during the 2017 ASH Annual Meeting.

Dr. Davids on Checkpoint Blockade Inhibition in Hematologic Malignancies After Stem Cell Transplant

December 10th 2017, 6:44am

ASH Annual Meeting and Exposition

Matthew S. Davids, MD, Associate Director, Dana-Farber Cancer Institute Center for Chronic Lymphocytic Leukemia, discusses a study that explored optimizing checkpoint blockade as a treatment for relapsed hematologic malignancies after allogenic hematopoietic cell transplantation.

Zanubrutinib Highly Active in Non-Hodgkin Lymphoma

December 10th 2017, 4:03am

ASH Annual Meeting and Exposition

The investigational BTK inhibitor zanubrutinib (BGB-3111) demonstrated promising clinical activity in patients with non-Hodgkin lymphoma.

Lenalidomide Plus Rituximab Safe and Effective as Initial Treatment for MCL

December 10th 2017, 2:03am

ASH Annual Meeting and Exposition

Lenalidomide (Revlimid) plus rituximab (Rituxan) is a feasible combination that is also safe and active, as initial and maintenance therapy for patients with mantle cell lymphoma.

Direct Oral Anticoagulant Prevents VTE Recurrence in Select Patients With Cancer

December 9th 2017, 9:32pm

ASH Annual Meeting and Exposition

Treatment using oral rivaroxaban (Xarelto) reduced venous thromboembolism (VTE) recurrence among patients with cancer, according to results from the select-d trial.

Antibody-Drug Conjugate Active in Heavily Pretreated Metastatic TNBC

December 9th 2017, 3:35am

San Antonio Breast Cancer Symposium

Monotherapy with an antibody drug conjugate targeting the transmembrane protein LIV-1 had encouraging antitumor activity in a phase 1 study of patients with heavily pretreated TNBC.

Gene-Based Biomarker Identifies Patients With Breast Cancer More Likely to Respond to Enzalutamide

December 9th 2017, 2:44am

San Antonio Breast Cancer Symposium

Enzalutamide (Xtandi) added to exemestane improved progression-free survival in patients with hormone receptor-positive advanced breast cancer and no prior endocrine therapy who were positive for a gene signature-based biomarker indicating androgen receptor-signaling.

Trastuzumab Deruxtecan Impresses in HER2 Expressing Breast Cancers

December 9th 2017, 1:59am

San Antonio Breast Cancer Symposium

Trastuzumab deruxtecan (ds-8201a), a HER2-targeting antibody-drug conjugate, demonstrated significant clinical activity in heavily pretreated patients with HER2-expressing metastatic breast cancers.

Positive CTC Findings Linked to High Recurrence Risk in HR+ Breast Cancer

December 9th 2017, 1:38am

San Antonio Breast Cancer Symposium

Detection of positive circulating tumor cells in the blood 5 years after a breast cancer diagnosis was associated with an increased risk for late recurrence in women with HR–positive, HER2-negative breast cancer

Pembrolizumab/Eribulin Efficacy Maintained for TNBC in Larger Dataset

December 9th 2017, 12:58am

San Antonio Breast Cancer Symposium

Treatment with the combination of pembrolizumab (Keytruda) and eribulin (Halaven) demonstrated a 26.4% objective response rate for patients with metastatic triple-negative breast cancer.

Dr. Burstein Discusses Key Updates from the SOFT Trial

December 9th 2017, 12:57am

San Antonio Breast Cancer Symposium

Harold Burstein, MD, PhD, medical oncologist, Dana-Farber Cancer Institute discusses some key findings from the follow-up data from the SOFT trial.