Latest Conference Articles

The OncLive® Conference page includes a listing of all conferences covered by OncLive®, including the ASCO, ESMO, SITC, EHA, ASH, and SABCS annual meetings, as well as the Chemotherapy Foundation Symposium and Miami Breast Cancer Conference, among many others. Conference coverage incorporates articles and interviews in written and video format.

Ibrutinib, Ublituximab, TGR-1202 Triplet Active in Relapsed B-Cell Malignancies

June 19th 2015, 2:14pm

International Conference on Malignant Lymphoma

A chemotherapy-free combination of the anti-CD20 antibody ublituximab, ibrutinib, and the PI3K delta inhibitor TGR-1202 demonstrated robust clinical activity in patients with relapsed/refractory chronic lymphocytic leukemia or B-cell non-Hodgkin lymphoma.

PI3Kδ and JAK1 Inhibitors Show Promise in Advanced Hodgkin Lymphoma

June 19th 2015, 1:12pm

International Conference on Malignant Lymphoma

The PI3Kδ inhibitor INCB040093 alone or in combination with the JAK1 inhibitor INCB039110 showed early promise in relapsed/refractory classical Hodgkin lymphoma.

Dr. O'Brien Discusses Ibrutinib and Idelalisib in CLL

June 19th 2015, 11:01am

International Conference on Malignant Lymphoma

Susan M. O'Brien, MD, associate director, Clinical Science Medical Director of the Sue and Ralph Stern Center for Cancer Clinical Trials and Research, Chao Family Comprehensive Cancer Center, University of California at Irvine, discusses the use of ibrutinib and idealisib in chronic lymphocytic leukemia (CLL).

Nivolumab Elicits Durable Responses in Lymphoma

June 19th 2015, 8:04am

International Conference on Malignant Lymphoma

Nivolumab continued to show high activity and a good safety profile after more than a year of follow-up in heavily pretreated patients with relapsed or refractory lymphoid malignancies or those with classical Hodgkin lymphoma.

Rituximab, Thiotepa, and Chemo Combo Improves Outcomes in Primary CNS Lymphoma

June 18th 2015, 12:35pm

International Conference on Malignant Lymphoma

The MATRIX regimen, comprised of a methotrexate/cytarabine backbone plus thiotepa and rituximab, improved outcomes in patients with primary CNS lymphoma.

SYK Inhibitor TAK-659 Shows Promising Results in Lymphoid Malignancies

June 18th 2015, 12:05pm

International Conference on Malignant Lymphoma

TAK-659, an inhibitor of spleen tyrosine kinase, showed early signs of antitumor activity in patients with lymphoma, with two expansion arms planned for patients with diffuse large B-cell lymphoma and chronic lymphocytic leukemia.

Dr. Uldrick on Rituximab Plus Liposomal Doxorubicin in HIV-Infected Patients With KSHV-MCD

June 18th 2015, 11:26am

International Conference on Malignant Lymphoma

Thomas S. Uldrick, MD, staff clinician, HIV and AIDS Malignancy Branch, Center for Cancer Research at the National Institutes of Health, discusses long-term data from a study examining rituximab plus liposomal doxorubicin in HIV-infected patients with Kaposi sarcoma (KS) herpes virus-associated multicentric Castleman disease.

Interim FDG-PET Scans Enable Response-Adapted Therapy in Hodgkin Lymphoma

June 18th 2015, 6:37am

International Conference on Malignant Lymphoma

Interim PET-CT scanning was successfully used to adapt treatment regimens in patients with advanced classical Hodgkin lymphoma.

Dr. Adrian Wiestner on RESONATE II Trial

June 17th 2015, 3:07pm

International Conference on Malignant Lymphoma

Adrian Wiestner, MD, PhD, Senior Investigator, Laboratory of Lymphoid Malignancies, National Institutes of Health, National Heart, Lung, and Blood Services discusses the findings of the RESONATE II trial, which looked at chlorambucil versus ibrutinib as first-line therapy in patients older than 65 with chronic lymphocytic leukemia (CLL).

Lenvatinib Plus Everolimus Improves Survival in mRCC

June 5th 2015, 1:23pm

ASCO Annual Meeting

The combination of lenvatinib and everolimus more than doubled progression-free survival and extended overall survival by 10.1 months compared with everolimus alone as a second-line treatment for patients with metastatic renal cell carcinoma.

Dr. Van Tine on Trabectedin for Leiomyosarcoma and Liposarcoma

June 3rd 2015, 2:35pm

ASCO Annual Meeting

Brian A. Van Tine, MD, PhD, Assistant Professor Department of Medicine Siteman Cancer Center, Washington University School of Medicine, discusses trabectedin (Yondelis) for the treatment of soft tissue sarcomas.

Carfilzomib Tops Bortezomib in Relapsed Myeloma

June 3rd 2015, 1:29pm

ASCO Annual Meeting

Progression-free survival in relapsed myeloma doubled among patients treated with carfilzomib, rather than bortezomib, in combination with dexamethasone, a randomized trial showed.

Dr. Brufsky on Anastrozole Versus Tamoxifen in DCIS

June 3rd 2015, 12:01pm

ASCO Annual Meeting

Adam M. Brufsky, MD, PhD, professor of Medicine, associate chief, Division of Hematology/Oncology, co-director, Comprehensive Breast Cancer Center, associate director, Clinical Investigation, University of Pittsburgh, compares the use of anastrozole to tamoxifen in patients with ductal carcinoma in situ (DCIS).

Dr. Cristofanilli on the PALOMA3 Trial for Breast Cancer

June 3rd 2015, 11:04am

ASCO Annual Meeting

Massimo Cristofanilli, MD, Jefferson University Physician, professor, director, Breast Care Center, discusses the PALOMA3 trial.

PD-1/PD-L1 Inhibitors Safe, Effective in Advanced Ovarian Cancer

June 3rd 2015, 9:44am

ASCO Annual Meeting

Monoclonal antibodies against PD-1 and PD-L1 have demonstrated encouraging signs of antitumor activity for patients with pretreated advanced ovarian cancer.

Trabectedin Extends PFS in Phase III Soft Tissue Sarcoma Study

June 3rd 2015, 9:04am

ASCO Annual Meeting

Trabectedin reduced the risk of disease progression by 45% versus dacarbazine in patients with advanced soft tissue sarcoma.

Dr. Sandler on Docetaxel With Hormonal and Radiation Therapy in Prostate Cancer

June 2nd 2015, 4:36pm

ASCO Annual Meeting

Howard Sandler, MD, MS, FASTRO, chair, Radiation Oncology, Ronald H. Bloom Family Chair in Cancer Therapeutics, discusses results from a phase III study on docetaxel with hormonal and radiation therapy in prostate cancer.

Dr. Socinski on Nivolumab in NSCLC

June 2nd 2015, 9:52am

ASCO Annual Meeting

Mark A. Socinski, MD, professor of Medicine and Cardiothoracic Surgery, director, Lung Cancer Section, Division of Hematology/Oncology, clinical associate director, Lung SPORE, co-director, UPMC Lung Cancer Center of Excellence, co-leader, UPCI Lung Cancer Program, discusses a phase III study which examined nivolumab in non-small cell lung cancer (NSCLC).

Dr. Wolchock on the Phase III CheckMate-067 Melanoma Findings

June 2nd 2015, 9:23am

ASCO Annual Meeting

Jedd Wolchok, MD, PhD, chief, melanoma and immunotherapeutics service and Lloyd J. Old Chair for clinical investigation at Memorial Sloan Kettering Cancer Center, discusses the findings of the Phase III CheckMate-067 trial.

Neratinib Reduces HER2+ Breast Cancer Recurrences in Phase III ExteNET Study

June 2nd 2015, 5:57am

ASCO Annual Meeting

Treatment with neratinib immediately following adjuvant trastuzumab plus chemotherapy modestly improved invasive disease-free survival against placebo at the cost of low-grade diarrhea in almost all patients with HER2-positive early-stage breast cancer.