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Latest Conference Articles
The OncLive® Conference page includes a listing of all conferences covered by OncLive®, including the ASCO, ESMO, SITC, EHA, ASH, and SABCS annual meetings, as well as the Chemotherapy Foundation Symposium and Miami Breast Cancer Conference, among many others. Conference coverage incorporates articles and interviews in written and video format.
PD-L1 Inhibitor Avelumab Active in Advanced Mesothelioma
June 7th 2016, 1:57am
Avelumab demonstrated clinical activity in patients with advanced or unresectable mesothelioma, with an overall response rate of 14.3%.
Nivolumab Improves OS, ORR in Phase III Head and Neck Cancer Study
June 7th 2016, 1:13am
Treatment with single-agent nivolumab improved overall survival and objective response rates compared with investigator's choice of therapy for patients with recurrent or metastatic head and neck squamous cell carcinoma.
Black Women Who Are BRCA Carriers Less Likely to Pursue Breast and Ovarian Cancer Risk Reduction
June 7th 2016, 12:15am
Young black women with breast cancer are much less likely to have BRCA testing or, if they carry a BRCA mutation, to undergo risk-reducing prophylactic mastectomy or salpingo-oophorectomy.
Despite Recommendations, Aggressive Cancer Treatment Still Common at End of Life
June 6th 2016, 11:56pm
An analysis of over 28,000 patients younger than 65 with incurable cancers found that approximately three-fourths of them received aggressive care within the last 30 days of life and one-third died in the hospital.
Web App Boosts Survival for Lung Cancer Patients
June 6th 2016, 11:46pm
Patients with lung cancer who participated in a web-based system for reporting and tracking their symptoms achieved dramatic gains in survival compared with individuals who were followed with typical protocols.
Cancer Drugs Less Affordable in Poorer Countries Despite Lower Prices
June 6th 2016, 10:26pm
Researchers who set out to understand the affordability of cancer drugs across the globe concluded that lower prices in some poorer countries don’t equate to better access.
Dabrafenib/Trametinib Combo Highly Effective in BRAF-Mutant NSCLC
June 6th 2016, 8:33pm
The combination of dabrafenib and trametinib was highly effective as a treatment for patients with BRAF V600E-mutant non–small cell lung cancer.
Nivolumab Delivers Durable Responses in Hodgkin Lymphoma
June 6th 2016, 7:35pm
Single-agent nivolumab induced responses in 66% of patients with classical Hodgkin lymphoma who had progressed following autologous stem cell transplant and brentuximab vedotin.
Nivolumab 5-Year OS Rate Passes 30% in Advanced RCC
June 6th 2016, 5:15am
About one third of patients with advanced renal cell carcinoma who were treated with single-agent nivolumab in the second-line setting or later were still alive at 4 and 5 years in long-term follow-up data from phase I and phase II clinical trials.
Atezolizumab Effective in First-Line Setting in Bladder Cancer
June 6th 2016, 3:29am
Patients with metastatic urothelial carcinoma who were ineligible for standard cisplatin-based chemotherapy achieved a 24% reduction in tumor size and had a median survival of 14.8 months after taking the immunotherapy agent atezolizumab (Tecentriq).
Bernard Fox on Significance of Immunoscore Validation Project
June 6th 2016, 3:21am
Bernard A. Fox, PhD, chief, Laboratory of Molecular and Tumor Immunology, Earle A. Chiles Research Institute at Providence Portland Medical Center, discusses the significance of the Immunoscore Validation Project.
Extending AI Therapy Beyond 5 Years Reduces Recurrence in HR-Positive Breast Cancer
June 6th 2016, 2:33am
Women who extended their adjuvant therapy with an aromatase inhibitor to 10 years after treatment for their early-stage HR-positive breast cancer reduced their risk of recurrence by more than a third and experienced no new toxicities or worsening of quality of life.
Dr. Balar on IMvigor 210 Results for Metastatic Urothelial Carcinoma
June 6th 2016, 2:31am
Arjun V. Balar, MD, assistant professor, Department of Medicine, co-leader of the Genitourinary Cancers Program, discusses updated results of cohort 1 of the IMvigor 210 study, which examined the efficacy of atezolizumab as first-line therapy in patients with cisplatin-ineligible locally advanced/metastatic urothelial carcinoma.
Survival in Recurrent GBM Surpasses Historical Results with Gene Therapy
June 6th 2016, 1:58am
A novel antiangiogenic gene therapy, added to bevacizumab, led to significantly better overall survival in recurrent glioblastoma multiforme compared with historical patients treated with bevacizumab alone, a small phase II trial showed.
Novel Gastric Cancer Immunotherapy Scores Robust Phase II Results
June 6th 2016, 12:50am
IMAB362 reduced the risk of death or progression by approximately 50% when added to standard chemotherapy for patients with CLDN18.2-positive advanced gastric cancers.
Nivolumab/Ipilimumab Combo Active in Microsatellite Instability-High mCRC
June 6th 2016, 12:27am
Nivolumab (Opdivo) as a monotherapy and in combination with ipilimumab (Yervoy) demonstrated promising antitumor activity in patients with high microsatellite instability (MSI-H) metastatic colorectal cancer.
Rovalpituzumab Tesirine Shows Promising Efficacy for SCLC
June 6th 2016, 12:22am
Treatment with rovalpituzumab tesirine demonstrated single-agent activity and a manageable safety profile for patients with recurrent/refractory small cell lung cancer.
Daratumumab Combo Shows Unprecedented PFS Benefit in Multiple Myeloma
June 5th 2016, 9:44pm
Adding daratumumab to bortezomib and dexamethasone reduced the risk of progression or death by 61%, and doubled response rates compared with the standard 2-drug regimen alone for patients with recurrent or refractory multiple myeloma.
Adding Temozolomide to Radiotherapy Is Effective and Tolerable in Older Adults With Glioblastoma
June 5th 2016, 9:03pm
Adding temozolomide to short-course radiotherapy after surgery boosted overall survival by nearly 2 months, bringing 1-year survival rates up from 22.2% to 37.8% for elderly patients with glioblastoma.
Dr. Palumbo on CASTOR Trial Results in Multiple Myeloma
June 5th 2016, 8:02pm
Antonio Palumbo, MD, chief, Myeloma Unit, Department of Oncology, Section of Hematology, University of Torino, Italy, discusses the phase III results of the CASTOR trial, which was a randomized controlled study examining the efficacy of daratumumab (Darzalex), bortezomib (Velcade), and dexamethasone versus bortezomib and dexamethasone in patients with relapsed or refractory multiple myeloma.