Post-Conference Perspectives: CD19-directed CAR-T Cell Therapy in Lymphomas

Loretta J. Nastoupil, MD, and Marc S. Hoffman, MD, review key updates on the role of CAR T-cell therapy in large B-cell lymphoma (LBCL), follicular lymphoma, and non-Hodgkin’s lymphoma, and discuss how the data applies to clinical practice.

EP. 1: Overview of Relapsed/Refractory Diffuse Large B-Cell Lymphoma (R/R DLBCL)

January 23rd 2023

Marc S. Hoffman, MD, provides an overview of recent updates in the treatment of relapsed/refractory diffuse large B-cell lymphoma.

EP. 2: Currently Available Treatment Options for Patients With R/R DLBCL

January 23rd 2023

Drs Loretta J. Nastoupil and Marc S Hoffman explain the available treatment options for relapsed/refractory diffuse large B-cell lymphoma and what to consider when selecting a therapy in the second-line setting.

EP. 3: ZUMA-7: Axicabtagene Ciloleucel as a Second-Line Therapy for LBCL

January 30th 2023

Loretta J. Nastoupil, MD, reviews data from the ZUMA-7 trial investigating the use of axicabtagene ciloleucel as a second-line therapy for large b-cell lymphoma.

EP. 4: Is There a Potential Role for Rapcabtagene Autoleucel in R/R LBCL?

February 7th 2023

Experts discuss data on a novel form of CAR T-cell therapy, rapcabtagene autoleucel, for the second-line treatment of R/R LBCL with a faster manufacturing process.

EP. 5: Selecting the Appropriate CAR T-Cell Therapy for Patients with R/R LBCL

February 7th 2023

Marc S. Hoffman, MD, explains how to select the appropriate CAR T-cell therapy for each patient, and the barriers patients with R/R LBCL face in receiving CAR T-cell therapy, despite its high efficacy rate.

EP. 6: Available Treatment Options for Relapsed/Refractory Follicular Lymphoma (R/R FL)

February 13th 2023

Dr Marc S Hoffman reviews the currently available treatment options for relapsed/refractory follicular lymphoma.

EP. 7: CAR T-Cell Therapy for Patients With R/R FL

February 13th 2023

A discussion on which patients with relapsed/refractory follicular lymphoma are good candidates for CAR T-cell therapy.

EP. 8: Utilizing CAR T-Cell Therapy in the Treatment of Relapsed/Refractory Mantle Cell Lymphoma

February 20th 2023

Wrapping up their discussion, Loretta J. Nastoupil, MD, and Marc S. Hoffman, MD, look at the use of CAR T-cell therapy for patients with mantle cell lymphoma, a rare subtype of non-Hodgkin’s lymphoma.