ZUMA-3: CAR T Therapy for Adult Patients With ALL

Key opinion leaders in hematology oncology, Eunice Wang, MD and Bijal Shah, MD, MS, review the results of the ZUMA trial of CAR T cell therapy in adult patients with relapsed/refractory ALL. 

EP. 1: The Evolving Treatment Landscape for ALL 

June 30th 2021

Eunice Wang, MD and Bijal Shah, MD, MS, begin with an overview of novel agents and emerging therapeutic approaches for the treatment of acute lymphoblastic leukemia.  

EP. 2: Using MRD to Monitor Therapeutic Response in  ALL 

June 30th 2021

Key experts in hematology oncology discuss the use of MRD status to assess therapeutic response and guide treatment decisions in patients with relapsed/refractory ALL.  

EP. 3: The ZUMA-3 Trial: Study Design and Patient Population

July 7th 2021

Leukemia experts provide an overview of the ZUMA-3 trial of chimeric antigen receptor (CAR) T-cell therapy in adult patients with relapsed/refractory acute lymphocytic leukemia (ALL) by discussing the overall study design and patient population.

EP. 4: The ZUMA-3 Trial: Efficacy and Safety Results

July 7th 2021

Primary investigator Bijal Shah, MD, MS, shares insights into the efficacy results of the ZUMA-3 trial of chimeric antigen receptor (CAR) T-cell therapy for acute lymphocytic leukemia (ALL), and Eunice Wang, MD, reviews the trial’s key safety data.

EP. 5: The ZUMA-3 Trial: Clinical Endpoints

July 7th 2021

Thought leaders in the management of ALL discuss the use of clinical endpoints like CR, CRi, and CRh as they relate to the ZUMA-3 trial of CAR T cell therapy, and lead trial author Bijal Shah, MD, MS, comments on the future application of MRD status.

EP. 6: The Potential Future Impact of CAR T Cell Therapy in Adult ALL

July 7th 2021

Experts in hematology oncology consider unmet needs for adult patients with relapsed/refractory ALL and reflect on the potential impact that FDA approval of CAR T cell therapy would have on the treatment landscape.