My Treatment Approach: Colorectal Cancer | Supplements and Featured Publications

This publication covers some of the latest advances in colorectal cancer treatment following recent read outs from clinical trials, as well as expert insights on how they approach therapy on an individualized basis.

Biweekly Cetuximab Offers a Convenient Dosing Option in mCRC

July 27, 2021

Richard Kim, MD, discusses the utility of EGFR inhibitors in patients with RAS wild-type colorectal cancer, the convenience of biweekly dosing with cetuximab, recommendations for managing EGFR inhibitor–related treatment-related adverse effects, and novel combinations on the horizon.

GI Experts Discuss Treatment Dosing, Sequencing, and Future Directions in CRC

July 15, 2021

Jaffar A. Ajani, MD, and Zev A. Wainberg, MD, discuss FDA updates regarding the dosing schedule of cetuximab for metastatic colorectal cancer and the value of real-word data on clinical practice patterns in the community when administering this drug.

Genomics, Sidedness Guide Treatment Selection in Metastatic CRC

July 14, 2021

Zev A. Wainberg, MD, and Jaffer A. Ajani, MD, discuss how to best utilize information provided to inform treatment decisions, treatment approaches for patients with newly diagnosed RAS wild-type mCRC, and factors that affect influence selecting a 2- vs 3-drug chemotherapy regimen.

Future Directions in mCRC

June 22, 2021

Drs Jaffer A. Ajani and Zev A. Wainberg comment on current obstacles surrounding the treatment of metastatic colorectal cancer and consider the future use of ctDNA as more is learned about the disease.

Sequencing Anti-EGFR Therapy in mCRC

June 08, 2021

The importance of aligning second-line treatment decisions with patient goals in metastatic colorectal cancer, and the benefits of treating patients with biweekly cetuximab, especially during the COVID-19 pandemic.

Changes in Cetuximab Dosing Schedule in mCRC

June 08, 2021

Reactions to recent changes approved by the FDA to the dosing schedule of cetuximab for metastatic colorectal cancer and the value of real-word data on clinical practice patterns in the community when administering this drug.

Next-Generation Sequencing in Metastatic Colorectal Cancer

June 01, 2021

Drs Jaffer A. Ajani and Zev A. Wainberg comment on the rationale for conducting full next-generation sequencing panels on patients with metastatic colorectal cancer and explain how to best utilize information provided to inform treatment decisions.