Dr. Choueiri Highlights the Latest in Genitourinary Cancer Research

Toni Choueiri, MD, director, Lank Center for Genitourinary Oncology, director, Kidney Cancer Center, Jerome and Nancy Kohlberg Associate Professor of Medicine, Harvard Medical School, Dana-Farber Cancer Institute, discusses the latest treatments in genitourinary (GU) cancers.

At the 2018 State of Science Summit^TM on Genitourinary Cancers, Dr Bradley McGregor discussed the landscape of advanced renal cell carcinoma (RCC) and the use of targeted therapy and immunotherapy in treatment. Immunotherapy research includes combinations such as nivolumab (Opdivo) and ipilimumab (Yervoy) and other VEGF inhibitors. Many phase III trials are comparing the efficacy of these agents with sunitinib (Sutent). Many of these trials have completed enrollment or are ongoing, so there is much to come in advanced RCC, says Choueiri.

Dr Guru Sonpavde spoke about integrating immunotherapy into chemotherapy regimens in advanced bladder cancer in the early-stage setting. Additionally, Dr Xiao Wei spoke about the importance of systemic therapy management across GU cancers. The focus was on PD-1/PD-L1 inhibitors and immunotherapy in general in the management of adverse events.