Dr. Choueiri on Existing Therapies for Kidney Cancer

Toni Choueiri, MD, clinical director, Lank Center for Genitourinary Oncology, director, Kidney Cancer Center, senior physician, Dana-Farber Cancer Institute, discusses the current therapies for patients with kidney cancer.

Sunitinib (Sutent) remains a standard treatment in the first-line setting and is used as the control arm for multiple phase III trials. Pazopanib (Votrient) is a frontline standard therapy that is similar to sunitinib but may be better tolerated depending on the scheduling, states Choueiri.

There is a subgroup of patients that have certain mutations that are showing high response rates to everolimus (Afinitor), explains Choueiri.