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Keith Kerr, BSc, MB, ChB, FRCPath, FRCPE, of the University of Aberdeen, Aberdeen, Scotland, discusses patient selection for immunotherapy in lung cancer.
Patient selection for immunotherapy is a controversial topic, says Kerr. The community is concerned that PD-L1 is not the ideal biomarker and many oncologists would prefer not to have to select patients at all and just give PD-1 inhibitors to everyone, says Kerr.
However, this is unrealistic, for both medical and financial reasons, he says. If you look at healthcare on a global scale, it is not going to be feasible or practical to give these drugs to everyone, and so the search for a more effective biomarker must continue.