Dr. Pegram on Pertuzumab Plus Trastuzumab and Chemotherapy in Breast Cancer

Mark D. Pegram, MD, associate director, clinical research, director, Breast Cancer Program, Stanford Cancer Institute, discusses the current treatment landscape for patients with HER2-positive breast cancer.

Based on level 1 evidence, there is good data to support the use of pertuzumab (Perjeta) plus trastuzumab (Herceptin) with chemotherapy in the first line setting. This is then followed by T-DM1 in the second line, states Pegram.

This has set the standard of care for the HER2-postive metastatic breast cancer patient population, explains Pegram.