Dr. Sauter on CAR T Cells in Real-World Patients With Hematologic Malignancies

Craig Sauter, MD, a hematologic oncologist and clinical director of the Adult Bone Marrow Transplant Service at Memorial Sloan Kettering Cancer Center, discusses the anecdotal observational data in real-world patients with hematologic malignancies who received chimeric antigen receptor (CAR) T-cell therapy.

Patients are often faced with side effects such as severe cytopenia for long periods of time, says Sauter. If patients fail CAR T-cell therapy, further therapy becomes challenging. When patients progress, they must receive cytotoxic therapy with adequate hematopoietic reserve to tolerate the CAR T cells.