Dr. Yang on the Efficacy of Immunotherapy in Follicular Lymphoma

Zhi Zhang Yang, MD, assistant professor of Medicine, Mayo Clinic, discusses the expression of LAG-3 defining exhaustion of intratumoral PD-1 antibodies and T cells and correlates poor outcomes in patients with follicular lymphoma.

PD-1 therapy is very effective in Hodgkin lymphoma; however, it is not as effective in the solid tumor or other lymphoma subtypes, explains Yang.

Scientists are attempting to add more to immunotherapy to increase the efficacy for patients with follicular lymphoma, states Yang.