Oncology Business Management | Specialty

TRIBE Trial: First-Line Treatment of mCRC

September 29th 2013

The Cancer Therapy & Research Center at the University of Texas Health Science Center Joins OncLive's Strategic Alliance Partnership

September 25th 2013

World-class cancer research and treatment center is the latest to partner with OncLive to promote its research, events, and initiatives

Merrimack's GI Cancer Agents Show Promise

September 20th 2013

Merrimack Pharmaceuticals is combining biology, computing, and engineering in order to gain a comprehensive understanding of the dynamics of different types of cancer and then use that information to develop new therapeutics.

Volasertib Given Breakthrough Therapy Designation for AML

September 17th 2013

The novel PLK1 inhibitor volasertib in combination with low-dose cytarabine has received a Breakthrough Therapy designation from the FDA for its potential as a treatment for patients with untreated AML.

Dr. Bunn Discusses Afatinib in Lung Cancer

September 17th 2013

Paul A. Bunn, Jr, MD, professor of medicine in medical oncology, head of the division of medical oncology, University of Colorado, discusses afatinib for patients with activating epidermal growth factor receptor (EGFR) mutation.

First Generic Version of Capecitabine Gains FDA Approval

September 16th 2013

The FDA has approved the first generic formulation of capecitabine, an oral chemotherapeutic that is currently approved to treat patients with metastatic colorectal cancer and metastatic breast cancer.

Dabrafenib and Trametinib Combination Granted Priority Review Designation by FDA

September 16th 2013

The FDA has granted Priority Review designation to dabrafenib (Tafinlar) and trametinib (Mekinist) as a combination treatment for patients with unresectable or metastatic melanoma with a BRAFV600E/K mutation.

Ofatumumab Receives Breakthrough Therapy Designation for Earlier Use in CLL

September 16th 2013

The monoclonal antibody ofatumumab has received Breakthrough Therapy designation from the FDA that could allow for earlier use in patients with chronic lymphocytic leukemia.

Dr. Steensma on ODAC's Pertuzumab Decision

September 12th 2013

David P. Steensma, MD, from the Dana-Farber Cancer Institute, provides insight into the ODAC decision to recommend approval for a neoadjuvant pertuzumab-containing regimen for patients with HER2-positive breast cancer.

In Historic Vote, ODAC Suggests Approval of Neoadjuvant Pertuzumab Regimen

September 12th 2013

The FDA's Oncologic Drugs Advisory Committee voted 13-0 with one abstention in support of pertuzumab in combination with trastuzumab and docetaxel for patients with HER2-positive breast cancer in the neoadjuvant setting.

Breakthrough Designation Granted to Entinostat for Advanced Breast Cancer

September 11th 2013

The novel HDAC inhibitor entinostat in combination with exemestane has received a Breakthrough Therapy designation from the FDA for its potential to reverse resistance to hormonal therapies used to treat patients with advanced ER-positive breast cancer.

Sequester Cuts to Cancer Care May Cost Taxpayers More in the End

September 9th 2013

The federal sequester trims Medicare payments for cancer patients receiving chemotherapy in doctors' offices in an effort to save the government money. Instead, it will end up costing more in the long run, according to the president of ASCO.

FDA Approves Nab-Paclitaxel for Advanced Pancreatic Cancer

September 6th 2013

The FDA has approved nab-paclitaxel plus gemcitabine as a first-line treatment for patients with metastatic adenocarcinoma of the pancreas, an area of high unmet need with few effective treatments.

Puma Begins Phase III Development of Neratinib in Breast Cancer

September 6th 2013

Puma Biotechnology is a Los Angeles-based development stage biopharmaceutical company that has spent the last couple of years focused on the development of its lead drug candidate, neratinib (PB272).

The Affordable Care Act: What Nurses Need to Know

September 5th 2013

A hot topic of discussion at the American Society of Clinical Oncology (ASCO) meeting in June was the Patient Protection and Affordable Care Act (often referred to as the ACA) and what it means for the future of oncology care in the United States.

Novel Drug Studies Yield Biomarker Candidates for Prostate Cancer Bone Turnover

September 4th 2013

Prostate cancer has a propensity to metastasize to bone. High turnover ultimately results in a net loss of bone tissue; prostate cancer treatment contributes to the loss of bone integrity, as androgen- deprivation therapy often causes abnormally low bone density

Sorafenib Receives Priority Review for Rare Thyroid Cancer

August 27th 2013

The FDA has given priority review designation to sorafenib for the treatment of locally advanced or metastatic RAI-refractory differentiated thyroid cancer.

Taking Care of Business: Regional Urology Offers Consistent Care Despite Tumultuous Times

August 22nd 2013

Change may not always be pleasant, but it is inevitable, and nowhere has that been more evident recently than in US healthcare; however, for the physicians at Regional Urology in Shreveport, Louisiana, these changes are really just business as usual.

Dr. Van Tine on Identifying Biomarkers in Sarcomas

August 12th 2013

Brian A. Van Tine, MD, PhD, Assistant Professor, Washington University School of Medicine in St. Louis, discusses identifying biomarkers in sarcomas.

Dr. Saenger on the Need for Immunotherapy Biomarkers

August 7th 2013

Yvonne M. Saenger, MD, Assistant Professor in Medicine and Dermatology, Hematology and Medical Oncology, Mount Sinai School of Medicine, discusses the need for biomarkers for immunotherapies.