Latest Conference Articles

The OncLive® Conference page includes a listing of all conferences covered by OncLive®, including the ASCO, ESMO, SITC, EHA, ASH, and SABCS annual meetings, as well as the Chemotherapy Foundation Symposium and Miami Breast Cancer Conference, among many others. Conference coverage incorporates articles and interviews in written and video format.

Broader Trial Criteria Would Almost Double Eligibility in Advanced NSCLC

June 3rd 2019, 3:35pm

ASCO Annual Meeting

A broader set of clinical trial eligibility criteria proposed by the American Society of Clinical Oncology and Friends of Cancer Research would nearly double the number of patients with advanced non-small cell lung cancer available for enrollment.

Enfortumab Vedotin Produces Responses in Patients With Advanced Urothelial Carcinoma

June 3rd 2019, 3:34pm

ASCO Annual Meeting

Enfortumab vedotin induced responses in 44% of patients with locally advanced or metastatic urothelial cancer, including 12% experiencing a complete response to treatment.

Dr. Golan on the Phase III POLO Trial in BRCA-Mutant Pancreatic Cancer

June 3rd 2019, 4:44am

ASCO Annual Meeting

Talia Golan, MD, head of Sheba Pancreatic Cancer Center, discusses the results of the phase III POLO trial, which evaluated maintenance olaparib compared with placebo among patients with germline BRCA-mutated metastatic pancreatic cancer.

Dr. Sweeney on the Phase III ENZAMET Trial in Metastatic Hormone-Sensitive Prostate Cancer

June 3rd 2019, 4:03am

ASCO Annual Meeting

Christopher Sweeney, MBBS, medical oncologist at the Lank Center for Genitourinary Oncology, Dana-Farber Cancer Institute, discusses results of the phase III ENZAMET trial, which looked at standard therapy with or without enzalutamide as a treatment for patients with metastatic hormone-sensitive prostate cancer.

Isatuximab Triplet Significantly Improves PFS in Myeloma

June 3rd 2019, 3:10am

ASCO Annual Meeting

Adding isatuximab to pomalidomide and low-dose dexamethasone led to a greater than 40% reduction in the risk of disease progression or death compared with pomalidomide and dexamethasone alone in patients with relapsed/refractory multiple myeloma.

Subcutaneous Daratumumab Shows Similar Efficacy, Greater Convenience in Phase III Myeloma Trial

June 3rd 2019, 12:29am

ASCO Annual Meeting

A subcutaneous flat-dose version of daratumumab demonstrated noninferior efficacy with a reduction in the treatment burden compared with the original intravenous formulation of the anti-CD38 monoclonal antibody for patients with relapsed/refractory multiple myeloma.

High TMB Metastatic Breast Cancer Responds to Pembrolizumab Monotherapy

June 2nd 2019, 11:54pm

ASCO Annual Meeting

Examination of a cohort of patients with metastatic breast cancer and high mutational burden who were enrolled in the phase II Targeted Agent and Profiling Utilization Registry basket study shows that pembrolizumab monotherapy has antitumor activity in this population of heavily pretreated patients.

Lurbinectedin Shows Promise as Single-Agent in Second-Line SCLC

June 2nd 2019, 4:34pm

ASCO Annual Meeting

Lurbinectedin monotherapy achieved an overall response rate of 35.2% as a second-line treatment for patients with small cell lung cancer, according to findings from a phase II basket trial presented at the 2019 ASCO Annual Meeting.

Maintenance Olaparib Improves PFS in BRCA+ Metastatic Pancreatic Cancer

June 2nd 2019, 3:31pm

ASCO Annual Meeting

Maintenance therapy with olaparib significantly improved progression-free survival compared with placebo among patients with germline BRCA-mutated metastatic pancreatic cancer.

Enzalutamide Increases Survival in mHSPC Over Other Anti-Androgens

June 2nd 2019, 3:31pm

ASCO Annual Meeting

Almost 80% of men with metastatic hormone-sensitive prostate cancer treated with enzalutamide plus standard of care (SOC) were alive after 3 years compared with 72% of patients who received a different non-steroidal anti-androgen plus SOC.

Alarm Sounded Over Multiple Myeloma Outcomes Versus Socioeconomics

June 2nd 2019, 3:30pm

ASCO Annual Meeting

Higher income was associated with significantly greater probability of survival for patients with multiple myeloma, according to authors of a study they performed to call attention to the need to address socioeconomic disparities that influence treatment outcomes.

Medicaid Expansion Helps Reduce Racial Disparities in Access to Cancer Care

June 2nd 2019, 3:30pm

ASCO Annual Meeting

The expansion of Medicaid nearly eliminated racial disparities in time to cancer treatment.

ACA Improved Ovarian Cancer Diagnosis and Time to Treatment

June 2nd 2019, 3:30pm

ASCO Annual Meeting

Pre-Medicare-aged women with ovarian cancer were more likely to be diagnosed at an early stage and receive treatment within 30 days of diagnosis after passage of the Affordable Care Act than before.

Dr. Chi on the TITAN Trial Results in Metastatic Castration-Sensitive Prostate Cancer

June 2nd 2019, 4:24am

ASCO Annual Meeting

Kim N. Chi, MD, associate director of clinical research, Vancouver Prostate Centre, professor, Department of Medicine, University of British Columbia, discusses the results of the phase III TITAN trial, which evaluated apalutamide versus placebo (PBO) in patients (pts) with metastatic castration-sensitive prostate cancer (mCSPC) receiving androgen deprivation therapy (ADT).

Dr. Tripathy Discusses the MONALEESA-7 Trial in HR+ Breast Cancer

June 2nd 2019, 3:23am

ASCO Annual Meeting

Debu Tripathy, MD, professor and chairman, Department of Breast Medical Oncology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, discusses the MONALEESA-7 trial in hormone receptor-positive breast cancer.

Open Source System Debuts for EHR Data Sharing

June 2nd 2019, 1:54am

ASCO Annual Meeting

A consortium of cancer care institutions released details on a prototype system designed to link electronic health record systems to provide a source of real-world patient information to guide research and improve cancer treatment.

New Strategies Needed for TKI Resistance in EGFR+ Lung Cancer

June 1st 2019, 11:04pm

ASCO Annual Meeting

The development of tyrosine kinase inhibitors has revolutionized the treatment of EGFR-mutant non–small cell lung cancer in recent years, but new strategies are needed to overcome resistance mechanisms that promote disease recurrence.

Apalutamide Extends Survival in Metastatic Castration-Sensitive Prostate Cancer

June 1st 2019, 8:33pm

ASCO Annual Meeting

Adding apalutamide to androgen deprivation therapy (ADT) reduced the risk of the death by 33% in patients with metastatic castration-sensitive prostate cancer compared with ADT alone.

Frontline Pembrolizumab Induces Comparable OS, Fewer AEs in Advanced GEJ Cancer

June 1st 2019, 3:32pm

ASCO Annual Meeting

Frontline pembrolizumab demonstrated non-inferior overall survival compared with standard chemotherapy among patients with PD-L1–positive, HER2-negative, advanced gastric or gastroesophageal junction cancer.

Ribociclib Improves Survival by Nearly 30% for Premenopausal Women With Advanced Breast Cancer

June 1st 2019, 3:32pm

ASCO Annual Meeting

Ribociclib plus endocrine therapy demonstrated an estimated overall survival rate of 70.2% at 42 months compared 46.0% for placebo and endocrine therapy in premenopausal women with HR-positive, HER2-negative advanced breast cancer.