Latest Conference Articles

The OncLive® Conference page includes a listing of all conferences covered by OncLive®, including the ASCO, ESMO, SITC, EHA, ASH, and SABCS annual meetings, as well as the Chemotherapy Foundation Symposium and Miami Breast Cancer Conference, among many others. Conference coverage incorporates articles and interviews in written and video format.

Kumar Discusses Path Forward for Venetoclax in Myeloma

September 16th 2019, 7:38pm

International Myeloma Society Annual Meeting

Shaji Kumar, MD, discusses the addition of the BCL-2 inhibitor venetoclax to the combination of bortezomib and dexamethasone significantly improved progression-free survival, overall response rate, very good partial response, and minimal residual disease negativity rates in the phase III BELLINI trial in relapsed/refractory patients with multiple myeloma.

Melflufen Regimen Elicits Activity in Relapsed Myeloma With Extramedullary Disease

September 16th 2019, 1:35am

International Myeloma Society Annual Meeting

Melflufen and dexamethasone demonstrated encouraging activity in patients with relapsed/refractory multiple myeloma with and without extramedullary disease, with response rates higher than those observed in prior studies of other agents.

Dr. Castillo on the Use of Venetoclax in Waldenstrom Macroglobulinemia

September 15th 2019, 11:35pm

International Myeloma Society Annual Meeting

Jorge J. Castillo, MD, clinical director, Bing Center for Waldenström Macroglobulinemia, physician, associate professor of medicine, Harvard Medical School, Dana-Farber Cancer Institute, discusses the results of a multicenter, prospective, phase II study of venetoclax in patients with previously treated Waldenstrom macroglobulinemia.

Dr. Usmani on Impact of BCMA on the Myeloma Treatment Landscape

September 15th 2019, 11:11pm

International Myeloma Society Annual Meeting

Saad Z. Usmani, MD, FACP, chief of Plasma Cell Disorder, director of Clinical Research in Hematologic Malignancies, Levine Cancer Institute, Atrium Health, discusses how the target BCMA is impacting the multiple myeloma treatment landscape.

Daratumumab Plus VRd Shows Improved sCR in Transplant-Eligible, Newly Diagnosed Myeloma

September 15th 2019, 10:56pm

International Myeloma Society Annual Meeting

The addition of daratumumab to bortezomib, lenalidomide, and dexamethasone for transplant-eligible patients with newly diagnosed multiple myeloma improved the depth of response without affecting stem cell mobilization or hematopoietic reconstitution.

Iberdomide Shows Promise in Heavily Pretreated Multiple Myeloma

September 15th 2019, 6:11pm

International Myeloma Society Annual Meeting

The novel agent iberdomide (formerly CC-220) was safe and showed antitumor activity when combined with dexamethasone in patients with heavily pretreated, relapsed/refractory multiple myeloma, according to findings from a phase Ib/IIa study presented at the 17th International Myeloma Workshop.

Novel Combos Are Shaking Up the CLL Landscape

September 15th 2019, 3:25am

Society of Hematologic Oncology Annual Meeting (SOHO)

The rise of oral targeted therapies and novel combinations is transforming the paradigm for the frontline treatment of patients with chronic lymphocytic leukemia regardless of age, and ongoing phase III trials are likely to generate more modifications.

Isatuximab Triplet Showcases Encouraging PFS in High-Risk Multiple Myeloma

September 15th 2019, 3:13am

International Myeloma Society Annual Meeting

Adding the CD38-directed monoclonal antibody isatuximab in combination with pomalidomide and dexamethasone improved progression-free survival in both standard-risk patients with relapsed/refractory multiple myeloma and those with high-risk cytogenetics.

Myelofibrosis Management Makes Strides With JAK Inhibitors, But Work Remains

September 15th 2019, 12:22am

Society of Hematologic Oncology Annual Meeting (SOHO)

Laura C. Michaelis, MD, discusses the currently approved JAK inhibitors and the future landscape for myelofibrosis, as well as treatment considerations for graft-versus-host disease.

Tisagenlecleucel Maintains Efficacy in Real-World Setting

September 15th 2019, 12:16am

Society of Hematologic Oncology Annual Meeting (SOHO)

Early results from a prospective postmarketing assessment showed that tisagenlecleucel induced responses similar to those seen in pivotal trials for children and adolescents with B-cell acute lymphoblastic leukemia and adults with diffuse large B-cell lymphoma.

Dr. William on Brentuximab Vedotin/Lenalidomide in T-Cell Lymphoma

September 14th 2019, 10:54pm

Society of Hematologic Oncology Annual Meeting (SOHO)

Basem William, MD, MRCP, FACP, discusses the preliminary results of the phase II trial of brentuximab vedotin and lenalidomide in relapsed/refractory cutaneous and peripheral T-cell lymphomas.

Isatuximab Quadruplet Active in High-Risk, Newly Diagnosed Myeloma

September 14th 2019, 8:53pm

International Myeloma Society Annual Meeting

A quadruplet regimen combining the anti-CD38 monoclonal antibody isatuximab with carfilzomib, lenalidomide, and dexamethasone was safe and had a 100% response rate among 10 patients enrolled in the safety run-in cohort of the phase II, multicenter GMMG-CONCEPT trial.

Dr. Yimer on Long-Term Proteasome Inhibition in Newly Diagnosed Myeloma

September 14th 2019, 7:49pm

International Myeloma Society Annual Meeting

Habte A. Yimer, MD, of Texas Oncology, discusses a real-world study evaluating the long-term use of proteasome inhibition in patients with multiple myeloma, and transitioning from bortezomib (Velcade) to ixazomib (Ninlaro).

Dr. Weisel on INSIGHT MM Analysis of Duration of Therapy in Myeloma

September 14th 2019, 7:40pm

International Myeloma Society Annual Meeting

Katja Weisel, MD, myeloma specialist at the University of Tübingen, discusses an analysis of the INSIGHT MM study evaluating fixed-duration versus continuous therapy for patients with multiple myeloma.

Daratumumab-VTd Regimen Shows Benefit in Newly Diagnosed High-Risk Multiple Myeloma

September 14th 2019, 6:57pm

International Myeloma Society Annual Meeting

Pieter Sonneveld, MD, PhD, discusses the significance of the subgroup analysis of the phase III CASSIOPEIA trial evaluating the regimen of daratumumab, bortezomib, thalidomide, and dexamethasone in patients with high-risk multiple myeloma.

Dr. Westin on Response Rates in the JULIET Trial for DLBCL

September 14th 2019, 5:05pm

Society of Hematologic Oncology Annual Meeting (SOHO)

Jason Westin, MD, discusses patient responses with relapsed/refractory diffuse large B-cell lymphoma in the JULIET trial who were treated with tisagenlecleucel.

Dr. Pui on Utilizing CAR T-Cell Therapy in Pediatric ALL

September 14th 2019, 2:49am

Society of Hematologic Oncology Annual Meeting (SOHO)

Ching-Hon Pui, MD, discusses the use of CAR T-cell therapy in patients with relapsed/refractory acute lymphocytic leukemia.

Update Spotlights Tisagenlecleucel Developments in DLBCL

September 14th 2019, 12:15am

Society of Hematologic Oncology Annual Meeting (SOHO)

Tisagenlecleucel maintained strong rates of response and duration of response in adults with relapsed/refractory diffuse large B-cell lymphoma, according to the latest findings from the phase II JULIET study presented at the 2019 SOHO Annual Meeting.

Despite Challenges, Targeted Cellular Therapies Continue to Be Explored in AML

September 13th 2019, 11:14pm

Society of Hematologic Oncology Annual Meeting (SOHO)

John F. DiPersio, MD, PhD, discusses the challenges in research surrounding targeted cellular therapies for acute myeloid leukemia

Checkpoint Inhibition Before HSCT Improves PFS Without Increasing Toxicity in R/R Hodgkin Lymphoma

September 13th 2019, 9:13pm

Society of Hematologic Oncology Annual Meeting (SOHO)

The use of checkpoint inhibitors prior to haploidentical stem cell transplantation improved progression-free survival and reduced the risk for relapse for patients with relapsed or refractory Hodgkin lymphoma, according to results from a retrospective study presented at the 2019 SOHO Annual Meeting.