Latest Conference Articles

The OncLive® Conference page includes a listing of all conferences covered by OncLive®, including the ASCO, ESMO, SITC, EHA, ASH, and SABCS annual meetings, as well as the Chemotherapy Foundation Symposium and Miami Breast Cancer Conference, among many others. Conference coverage incorporates articles and interviews in written and video format.

Hint of Survival Benefit With Olaparib in HER2-Negative/BRCA-Positive Metastatic Breast Cancer

April 16th 2018, 6:29pm

AACR Annual Meeting

Women with HER2-negative metastatic breast cancer associated with a germline BRCA mutation may have a slight survival advantage with a PARP inhibitor instead of chemotherapy.

Dr. Subbiah on Safety and Efficacy of BLU-667 in RET-Altered Solid Tumors

April 16th 2018, 1:49am

AACR Annual Meeting

Vivek Subbiah, MD, associate medical director, Clinical Center for Targeted Therapy, assistant professor, Department of Investigational Cancer Therapeutics, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, discusses the safety and efficacy findings of BLU-667 in RET-altered solid tumors in an interview during the 2018 AACR Annual Meeting.

Dr. Schoffski Discusses Findings from the CREATE Study

April 16th 2018, 1:44am

AACR Annual Meeting

Patrick Schöffski, MD, MPH, head of the Department of General Medical Oncology at the University Hospital Leuven, discusses the findings from the CREATE study during the 2018 AACR Annual Meeting.

Crizotinib Confirmed as Standard of Care for ALK+ Inflammatory Myofibroblastic Tumors

April 16th 2018, 12:00am

AACR Annual Meeting

Treatment with crizotinib elicited an objective response rate of 50% for patients with ALK-positive advanced, inoperable inflammatory myofibroblastic tumor.

BLU-667 Shows Promise for Advanced Solid Tumors With RET Alterations

April 15th 2018, 11:15pm

AACR Annual Meeting

BLU-667, a next-generation tyrosine kinase inhibitor, appeared to be well-tolerated and had broad clinical benefit among patients with advanced, RET-altered solid tumors who progressed on prior therapies.

Adjuvant Pembrolizumab Improves RFS in Stage III Melanoma

April 15th 2018, 10:53pm

AACR Annual Meeting

Adjuvant pembrolizumab (Keytruda) reduced the risk of recurrence or death by 43% in patients with resected, high-risk stage III melanoma, according to phase III results from the EORTC 1325-MG/KEYNOTE-054 trial.

QoL Data Support Durvalumab Use in Locally Advanced NSCLC

April 14th 2018, 11:54pm

European Lung Cancer Congress

Durvalumab treatment over 12 months had no negative effect on key symptoms of lung cancer, physical function, global health status, or quality of life in patients with locally advanced, unresectable stage III non–small cell lung cancer who have not progressed following concurrent chemoradiotherapy.

Dr. Yang on Resistance Mechanisms from Osimertinib in NSCLC

April 14th 2018, 11:41pm

European Lung Cancer Congress

James CH Yang, MD, PhD, Professor of Medicine, Deputy Director, Department of Medical Oncology, National Taiwan University Hospital, Director, Cancer Research, Center National Taiwan University College of Medicine, discusses resistance mechanisms that develop from treatment with osimertinib (Tagrisso) and other EGFR tyrosine kinase inhibitors (TKIs). Yang discussed this in an interview during the 2018 European Lung Cancer Congress, which is a joint collaboration between ESMO and the IASLC.

Post-Progression Data Establishes Osimertinib as Frontline Standard of Care for EGFR-Mutant NSCLC

April 14th 2018, 10:18pm

European Lung Cancer Congress

First-line treatment with osimertinib resulted in a clinically meaningful delay in time from randomization to second progression on subsequent treatment or death, establishing the agent as a new standard of care in the frontline setting for patients with EGFR-mutant non–small cell lung cancer.

Dr. Besse Discusses Challenges Facing Stage IV NSCLC

April 13th 2018, 11:35pm

European Lung Cancer Congress

Benjamin Besse, MD, Institut Gustave Roussy, Villejuif, Paris Sud University, discusses challenges facing the treatment of patients with stage IV non

Dr. Reck on the Rationale of the IMpower150 Trial in NSCLC

April 13th 2018, 11:33pm

European Lung Cancer Congress

Martin Reck, MD, Department of Thoracic Oncology, Lung Clinic Grosshansdorf, discusses the IMpower150 trial data for patients with non

Necitumumab/Abemaciclib Combo Fails in Stage IV NSCLC

April 13th 2018, 11:31pm

European Lung Cancer Congress

A phase Ib study of necitumumab in combination with abemaciclib failed to meaningfully improve outcomes in patients with stage IV non–small cell lung cancer.

Osimertinib Prevents CNS Progression in Advanced NSCLC in a Real-World Setting

April 13th 2018, 9:31pm

European Lung Cancer Congress

Patients with advanced non–small cell lung cancer and baseline central nervous system metastasis showed control of their CNS metastasis after receiving osimertinib in a real-world clinical setting.

Nivolumab Benefit Unresolved in Unresectable or Recurrent Thymic Cancer

April 13th 2018, 7:46pm

European Lung Cancer Congress

Researchers from Japan recommended against further development of nivolumab for patients with previously treated unresectable or recurrent thymic carcinoma based on their findings from the phase II PRIMER study.

Frontline Osimertinib Controls Symptoms for Patients With EGFR-Mutated NSCLC

April 13th 2018, 7:31pm

European Lung Cancer Congress

Frontline treatment with osimertinib led to similar improvements in quality of life, including a clinically meaningful improvement in cough, compared with a standard of care EGFR TKIs for patients with advanced EGFR-mutant non–small cell lung cancer.

Dr. Perol Discusses Results of the ALEX Trial in ALK+ NSCLC

April 12th 2018, 8:54pm

European Lung Cancer Congress

Maurice Perol, MD, medical oncologist, Centre Leon Berard, discusses the results of the ALEX trial in ALK-positive non–small cell lung cancer.

Dr. Garon Discusses the CheckMate-384 Study in NSCLC

April 12th 2018, 8:52pm

European Lung Cancer Congress

Edward B. Garon, MD, director of Thoracic Oncology at the Jonsson Comprehensive Cancer Center at University of California, Los Angeles, discusses the CheckMate-384 study in non–small cell lung cancer.

Dr. Garassino on QoL Findings from the FLAURA Study in NSCLC

April 12th 2018, 8:51pm

European Lung Cancer Congress

Marina Chiara Garassino, MD, medical consultant in the Medical Oncology Division, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy, discusses the quality of life findings from the FLAURA study in non–small cell lung cancer.

Alectinib Edge Over Crizotinib Supported by Patient-Reported Outcomes

April 12th 2018, 8:03pm

European Lung Cancer Congress

In findings consistent with earlier results on efficacy and adverse events reported for the phase III ALEX trial, investigators announced superior patient-reported outcomes for the next-generation tyrosine kinase inhibitor alectinib versus the standard of care TKI inhibitor crizotinib in ALK-positive non–small cell lung cancer.

Frontline Atezolizumab Combo Emerges as Potential New Standard in NSCLC

April 12th 2018, 7:36pm

European Lung Cancer Congress

The frontline regimen of atezolizumab (Tecentriq), bevacizumab (Avastin), carboplatin, and paclitaxel has emerged as a potential new standard of care for the treatment of patients with metastatic nonsquamous NSCLC.