Latest Conference Articles

The OncLive® Conference page includes a listing of all conferences covered by OncLive®, including the ASCO, ESMO, SITC, EHA, ASH, and SABCS annual meetings, as well as the Chemotherapy Foundation Symposium and Miami Breast Cancer Conference, among many others. Conference coverage incorporates articles and interviews in written and video format.

Cabozantinib Improves PFS Across High-Risk RCC Subgroups

January 4th 2016, 3:00pm

Genitourinary Cancers Symposium (ASCO GU)

Cabozantinib significantly improved progression-free survival versus everolimus in patients with renal cell carcinoma regardless of the degree of metastases, type or number of prior treatments, or patient risk status.

Palbociclib Improves Cell Cycle Control in ER-Positive Breast Cancer

December 14th 2015, 4:15pm

San Antonio Breast Cancer Symposium

Palbociclib enhances cell cycle control when added to anastrazole in the neoadjuvant setting in women with ER-positive primary breast cancer.

Pembrolizumab Continues to Show Promise in Breast Cancer

December 12th 2015, 10:04am

San Antonio Breast Cancer Symposium

The PD-1 inhibitor pembrolizumab had an overall response rate of 12% in PD-L1–positive patients with ER-positive/HER2-negative advanced breast cancer.

Neratinib DFS Benefit Sustained in 3-Year ExteNET Update

December 12th 2015, 8:25am

San Antonio Breast Cancer Symposium

The oral pan-HER TKI neratinib continued to show similar rates of disease-free survival for patients with HER2-positive early-stage breast cancer at a 3-year analysis of the phase III ExteNET trial.

Dr. Patricia Ganz on Anastrozole versus Tamoxifen Side Effects in DCIS Patients

December 11th 2015, 2:23pm

San Antonio Breast Cancer Symposium

Patricia Ganz, MD, UCLA Jonsson Comprehensive Cancer Center, discusses a study comparing anastrozole versus tamoxifen in patients with ductal carcinoma in situ (DCIS) breast cancer.

IBIS-II: Anastrozole and Tamoxifen Similar on Recurrence, but Toxicity Profiles Differ

December 11th 2015, 1:30pm

San Antonio Breast Cancer Symposium

Breast cancer recurrence was similar whether postmenopausal women with ductal carcinoma in situ received anastrozole or tamoxifen for 5 years following local excision in the IBIS-II trial.

Tamoxifen or Anastrozole? Patient Reports Can Help Decide

December 11th 2015, 1:18pm

San Antonio Breast Cancer Symposium

Patient reports of their experiences with taking either tamoxifen or anastrozole can help clinicians decide which one to recommend to individual women, new research has found.

Dr. Joanne Blum on the EMBRACA Trial in Metastatic BRCA-Mutant Breast Cancer

December 11th 2015, 11:47am

San Antonio Breast Cancer Symposium

Joanne Blum, MD, PhD, oncologist with Texas Oncology and a member of the Breast Cancer Committee for The US Oncology Network, discuses the EMBRACA trial.

T-DM1 Extends Survival in Heavily Pretreated HER2+ Breast Cancer

December 11th 2015, 10:35am

San Antonio Breast Cancer Symposium

T-DM1 (ado-trastuzumab emtansine; Kadcyla) reduced the risk of death by 32% and improved median overall surviva by almost 7 months compared with physician's choice of therapy in heavily pretreated patients with HER2-positive advanced breast cancer.

Buparlisib Modestly Improves PFS in HR-Positive Advanced Breast Cancer

December 11th 2015, 9:09am

San Antonio Breast Cancer Symposium

Treatment with the PI3K inhibitor buparlisib plus fulvestrant showed a 1.9-month extension in progression-free survival compared with fulvestrant alone in women with endocrine-resistant HR-positive/HER2-negative advanced breast cancer.

Dr. Saeed Rafii on Atezolizumab/ Nab-paclitaxel in TNBC

December 11th 2015, 6:09am

San Antonio Breast Cancer Symposium

Saeed Rafii, MD, PhD, medical director, Sarah Cannon Research Institute United Kingdom, discusses a study evaluating the safety and clinical activity of atezolizumab in combination with nab-paclitaxel in patients with metastatic triple-negative breast cancer (TNBC).

APOBEC3B Overexpression Linked to Tamoxifen Resistance

December 11th 2015, 6:08am

San Antonio Breast Cancer Symposium

The enzyme APOBEC3B has been associated with resistance to treatment with tamoxifen in retrospective studies and xenograft models of ER-positive breast cancer.

Estrogen Receptor Mutations Linked to Lower Survival in HR+/HER2- Breast Cancer

December 11th 2015, 6:04am

San Antonio Breast Cancer Symposium

Estrogen receptor mutations are prevalent and associated with poorer survival in patients with pretreated HR+/HER2- metastatic breast cancer.

Study Links pCR After Neoadjuvant Therapy to Improved Survival in TNBC

December 10th 2015, 5:14pm

San Antonio Breast Cancer Symposium

Achieving a pCR with standard neoadjuvant chemotherapy plus carboplatin and/or bevacizumab was associated with a survival improvement in patients with triple-negative breast cancer.

Complications, Costs Higher With Mastectomy Versus Lumpectomy for Early Breast Cancer

December 10th 2015, 2:46pm

San Antonio Breast Cancer Symposium

The risk of complications from mastectomy plus reconstruction was increased by two-fold compared with lumpectomy plus whole breast irradiation, after adjustment for other treatment differences.

Survival Better With Breast-Conserving Therapy Versus Mastectomy in Early-Stage Cancers

December 10th 2015, 1:22pm

San Antonio Breast Cancer Symposium

Women who opt for breast-conserving therapy and radiation to treat their early-stage breast cancer are about 20% more likely to be alive after 10 years compared with their counterparts who had mastectomy.

Reuben Harris on How Tamoxifen Resistance May be Driven by APOBEC3B

December 10th 2015, 12:59pm

San Antonio Breast Cancer Symposium

Reuben S. Harris, PhD, investigator Howard Hughes Medical Institute and professor in the Department of Biochemistry, Molecular Biology, and Biophysics at the University of Minnesota College of Biological Sciences, explains the role APOBEC3B may play in tamoxifen resistance in ER-positive breast cancer.

Atezolizumab/Nab-Paclitaxel Combo Shows High Response Rates in TNBC

December 10th 2015, 12:20pm

San Antonio Breast Cancer Symposium

Frontline treatment with the PD-L1 inhibitor atezolizumab combined with nab-paclitaxel showed a confirmed objective response rate of 66.7% in patients with metastatic triple-negative breast cancer.

Neoadjuvant Carboplatin Improves Disease-Free Survival in Triple-Negative Breast Cancer

December 10th 2015, 12:13pm

San Antonio Breast Cancer Symposium

Adding carboplatin to neoadjuvant chemotherapy improves disease-free survival significantly in women with triple-negative breast cancer but not HER2-positive breast cancer.

Dr. Whitworth on the Importance of Additional HER2 Subtyping

December 10th 2015, 7:06am

San Antonio Breast Cancer Symposium

Pat Whitworth, MD, medical oncologist at the Nashville Breast Center, discusses the prospective neo-adjuvant NBRST study, which looked at BluePrint functional subtyping versus conventional immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) in breast tumors.