Latest Conference Articles

The OncLive® Conference page includes a listing of all conferences covered by OncLive®, including the ASCO, ESMO, SITC, EHA, ASH, and SABCS annual meetings, as well as the Chemotherapy Foundation Symposium and Miami Breast Cancer Conference, among many others. Conference coverage incorporates articles and interviews in written and video format.

Pembrolizumab/Ipilimumab Combo Effective in Advanced Melanoma

November 22nd 2015, 11:27am

SMR Congress

A treatment regimen of pembrolizumab plus low-dose ipilimumab was tolerable and effective for patients with advanced melanoma.

Optimizing Precision Medicine Approaches in Glioblastoma

November 22nd 2015, 10:30am

Society for Neuro-Oncology Annual Meeting

The deployment of precision medicine to develop safe and effective therapies to treat malignant brain tumors is an effort that poses both opportunities and challenges.

'Groundbreaking' Global Brain Cancer Trial Planned

November 22nd 2015, 9:57am

Society for Neuro-Oncology Annual Meeting

An international coalition of experts is planning an innovative clinical trial aimed at speeding up the development of new treatments for patients with glioblastoma multiforme, putting into motion a biomarker-driven approach that has been employed in other malignancies.

Dr. Okada Discusses Immunotherapy Response Assessment in Neuro-Oncology

November 22nd 2015, 9:15am

Society for Neuro-Oncology Annual Meeting

Hideho Okada MD, PhD, discusses the need for a new immunotherapy response assessment in euro-oncology. Okada presented on this topic at the 2015 Annual Meeting of the Society for Neuro-Oncology.

Dr. Butowski on Real-Time Imaging of Nanoliposomal Irinotecan Injection

November 22nd 2015, 9:01am

Society for Neuro-Oncology Annual Meeting

Nicholas A. Butowski, MD, discusses an early-stage study of convection-enhanced delivery of nanoliposomal irinotecan with real-time imaging.

Early Research Signals Potential for CAR T-Cell Therapy in EGFRvIII-Positive GBM

November 22nd 2015, 8:15am

Society for Neuro-Oncology Annual Meeting

A pilot study of the efficacy of CAR T-cell therapy in patients with EGFRvIII-positive glioblastoma multiforme (GBM) has generated encouraging findings.

Factors Affecting Dabrafenib/Trametinib Outcomes in Melanoma Identified

November 22nd 2015, 7:17am

SMR Congress

In the largest-to-date analysis of treatment-naïve metastatic melanoma patients with BRAF V600 mutations treated with dabrafenib and trametinib, researchers have found that baseline LDH levels and number of disease sites were the most significant factors affecting survival.

Novel Pembrolizumab Combos Show Promising Responses in Melanoma

November 21st 2015, 4:11pm

SMR Congress

Two separate early phase clinical trials exploring pembrolizumab-containing immunotherapy combinations have shown objective response rates over 50% in patients with advanced melanoma.

Dr. Mrugala on Extending Treatment With Temozolomide in Glioblastoma

November 21st 2015, 2:01pm

Society for Neuro-Oncology Annual Meeting

Maciej M. Mrugala, MD, PhD, discusses a retrospective analysis looking at adding cycles of treatment with temozolomide in newly diagnosed patients with glioblastoma.

Rindopepimut Combo Continues to Show Strong OS Benefit in Relapsed GBM

November 21st 2015, 1:52pm

Society for Neuro-Oncology Annual Meeting

Treatment with the immunotherapy rindopepimut plus bevacizumab resulted in a 47% reduction in the risk of death compared with bevacizumab and a control for patients with relapsed glioblastoma multiforme.

Dr. Heimberger on FGL2 as a Regulator of Tumor-Mediated Immune Suppression

November 21st 2015, 12:58pm

Society for Neuro-Oncology Annual Meeting

Amy B. Heimberger, MD, discusses the potential of FGL2 as a multi-modality regulator of tumor-mediated immune suppression in patients with glioblastoma.

Understanding BRAF Resistance Critical to Advancing Melanoma Care

November 21st 2015, 12:12pm

SMR Congress

Making real strides in melanoma care requires an understanding of BRAF resistance mechanisms.

Promising Subgroup Data Leads to Phase III Immunotherapy Study for GBM

November 21st 2015, 10:38am

Society for Neuro-Oncology Annual Meeting

Findings from a subgroup of patients enrolled in a phase II study assessing the dendritic vaccine ICT-107 for patients with HLA-A2+ glioblastoma multiforme merit further exploration in a phase III study.

Dr. Georgina Long on Dabrafenib and Trametinib in BRAF-Mutated Melanoma

November 21st 2015, 10:02am

SMR Congress

Georgina Long, BSc, PhD, MBBS, FRACP, medical oncologist, translational researcher, Melanoma Institute Australia, The University of Sydney, discusses which patients may benefit from the combination of dabrafenib and trametinib based on several recent clinical trials.

June Provides Insight Into Managing AEs From CAR T-Cell Therapies

November 21st 2015, 9:46am

Society for Neuro-Oncology Annual Meeting

Though clinical work is ongoing and early, researchers are already considering how to manage potentially fatal neurotoxicities in patients treated with chimeric antigen receptor T-cell therapy

Dr. Atkinson on When to Use Nivolumab Monotherapy Versus Nivolumab/Ipilimumab Combination

November 21st 2015, 8:48am

SMR Congress

Victoria Atkinson, MD, of Princess Alexandra Hospital and Gallipoli Medical Research Foundation, Queensland, discusses long-term data from the phase III CheckMate-066 trial.

James Allison Predicts 'Cures' With Checkpoint Inhibitor Combinations

November 20th 2015, 3:41pm

SMR Congress

Since the approval of the first checkpoint inhibitor, ipilimumab, several combinations and monotherapies have gained rapid approval, with continued expansion on the horizon.

Dr. Sampson on Nivolumab Monotherapy for Recurrent Glioblastoma

November 20th 2015, 3:28pm

Society for Neuro-Oncology Annual Meeting

John H. Sampson, MD, PhD, MBA, MHSc, discusses results from cohort 1 of the CHECKMATE-143 trial.

Immune Checkpoint Inhibitors Hold Promise In Glioblastoma

November 20th 2015, 3:06pm

Society for Neuro-Oncology Annual Meeting

There are reasons to suggest that immune checkpoint inhibitors may be successful against central nervous system tumors, including glioblastoma.

Second-Line Optune Improves Survival in GBM

November 20th 2015, 2:28pm

Society for Neuro-Oncology Annual Meeting

The addition of Optune to chemotherapy and/or bevacizumab improved survival in patients with recurrent glioblastoma multiforme.