ASCO 2024: Updates in the Treatment of Advanced Renal Cell Carcinoma - Episode 5

Exciting Data and Trials in Progress from ASCO 2024

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Elizabeth Wulff-Burchfield, MD, facilitates a conversation about several clinical trials, such as STELLAR-001 and KEYNOTE-426, which investigate various treatment approaches for renal cell carcinoma (RCC).

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    EP. 1: Treatment Selection in the Frontline Setting of Advanced Clear Cell RCC
    EP. 2: Dr Wulff-Burchfield Reviews CheckMate 214 and CheckMate 9ER
    EP. 3: Dr Xu Reviews Data from the CLEAR Trial and Recent Analyses at ASCO 2024 - Lenvatinib + Pembrolizumab in Frontline Advanced RCC
    EP. 4: Dr Voss Shares Highlights from the COSMIC-313 and LITESPARK-024 Trials
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    EP. 5: Exciting Data and Trials in Progress from ASCO 2024
    EP. 6: Ongoing RCC Clinical Trials that may Impact Practice
    EP. 7: Dr Xu Provides Clinical Perspective on the CONTACT-03 Trial Outcomes
    EP. 8: Dr Voss Application of Updated KEYNOTE-564 Data
    EP. 9: Guiding Sequencing & Finding a Contemporary Regimen/ Approach to Treatment Post-Checkpoint Inhibition
    EP. 10: World Health Organization (WHO) Classification Updates for Papillary RCC
    EP. 11: Additional Forward-Looking Data and Studies Beyond Frontline Therapy in RCC
    EP. 12: The Role of Chemotherapy in nccRCC Treatment
    EP. 13: Select Ongoing Trials for nccRCC and Impact on the Treatment Landscape
    EP. 14: Final Thoughts/Looking Forward
    1. Please briefly discuss recent findings from ongoing trials and novel treatment strategies.
      1. STELLAR-001 single-agent zanzalintinib biomarker analysis (Pal et al, ASCO 2024)
      2. KEYNOTE-426 Phase 3 pembro + axitinib biomarker analysis (Rini et al., ASCO 2024 Abstract 4505)
      3. Phase 3 trial len + pembro + belzutifan/quavonlima (Choueiri, ASCO GU 2022: Abstract TPS399)
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