Optimizing CAR T-Cell Therapy in DLBCL With Community and Academic Perspectives - Episode 1

Integrating CAR T-Cell Therapy Into the Treatment Landscape for R/R DLBCL

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Experts discuss the role of chimeric antigen receptor T-cell therapy (CAR T) in the treatment landscape for relapsed/refractory diffuse large B-cell lymphoma (R/R DLBCL), how they sequence between bispecific antibodies and CAR T, the frequency and patient selection for CAR T in the second-line setting, and key takeaways from a recent oral presentation on real-world outcomes with axicabtagene ciloleucel (axi-cel) in the second-line setting from ASH 2024.

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    Video content above is prompted by the following:

    • Where does CAR T-cell therapy currently fall into your treatment landscape for R/R DLBCL ?
    • How are you sequencing between bispecific antibodies and CAR T in the treatment of DLBCL?
    • With the approval of 2 agents after first-line therapy, how frequently are you utilizing CAR T in the second-line setting, and for which patients?
    • There was a recent oral presentation about real-world outcomes with axi-cel in the second-line setting from ASH 2024. What are your key takeaways from it and has it impacted your decision-making?
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