Targeting NSCLC with Precision: Evaluation of the Emerging Role of Antibody-Drug Conjugates   - Episode 5

Navigating Between ADCs in NSCLC

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The panel examines the characteristics of patients with non-small cell lung cancer (NSCLC) without actionable alterations who might be the best candidates for frontline treatment with either sacituzumab govitecan or datopotamab deruxtecan (Dato-DXd) and identifies the persisting unmet needs for this patient population.

  1. Which patients without actionable alterations might be most suitable for sacituzumabgovitecan versus Dato-DXd in the frontline setting?
  2. What are the greatest remaining areas of unmet need in NSCLC without actionable mutations?
    1. Is there any emerging research that may help to address these needs?
    2. What are you most excited about in this space?