Expert Insights into the Efficacy and Safety of Brexucabtagene Autoleucel CART19 Cell Therapy in Adults with Advanced Acute Lymphoblastic Leukemia - Episode 4

Objectives, Clinical Endpoints, and Safety Profile of the Phase 2 ZUMA-3 Clinical Trial

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Dr. Bijal and colleagues discuss the objectives, clinical outcomes, and safety profile of the Phase 2 ZUMA 3 clinical trial, which evaluated treatment of adult patients with relapsed or refractory, B-precursor, acute lymphoblastic leukemia with the anti-CD-19/anti-CD20 bispecific CAR-T cell therapy, KTE-X19 (brexucabtagene autoleucel).

EP. 1: Faculty Introductions
EP. 2: Objectives of the 2023 ASH Insights Program on CAR-T Cell Therapy for Adult B Cell ALL
EP. 3: Overview of the Current State of CART19 Therapy for Adult Patients With R/R ALL
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EP. 4: Objectives, Clinical Endpoints, and Safety Profile of the Phase 2 ZUMA-3 Clinical Trial
EP. 5: Progression-Free Survival, Overall Survival, and the Prognostic Significance of Negative Minimal Residual Disease
EP. 6: Standardizing and Optimizing Bridging Strategies Prior to CAR-T Infusion
EP. 7: Outcomes of the Retrospective, Multicenter ROCCA Analysis (Real-World Outcomes Collaborative of CAR-T in Adult ALL)
EP. 8: Influences on Treatment Response and Survival in Recipients of Brexucabtagene Autoleucel Therapy
EP. 9: Optimal Sequencing of Therapy for Previously Treated Patients With Relapsed or Refractory ALL
EP. 10: Emerging Therapies for the Older Patient With Acute Lymphoblastic Leukemia