Expert Perspectives & Insights into CAR T-cell Therapy in Relapsed / Refractory Acute Lymphoblastic Leukemia   - Episode 18

Strategies and Resources for Overcoming Barriers to CAR T-Cell Therapy

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Acute lymphoblastic leukemia specialists explore resources and strategies to address the logistical hurdles of CAR-T therapy implementation, while also examining patient support programs designed to enhance treatment accessibility and adherence.

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  • Chapters
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    EP. 1: Overview of CAR T-cell Therapies in R/R B-cell ALL
    EP. 2: CAR T-cell Therapy: Mechanisms of Actions of Brexucabtagene Autoleucel and Obecabtagene Autoleucel
    EP. 3: Considerations for Dosing and Lymphodepletion with CAR T-cell Therapy in R/R ALL
    EP. 4: Expert Perspectives on CAR T-Cell Therapy Logistics: Collection to Treatment
    EP. 5: Overview of Available Treatment Options in R/R B-cell ALL
    EP. 6: Navigating CAR T-cell Therapy in R/R ALL: Expert Perspectives
    EP. 7: Expert Insights on ZUMA-3 Data Updates: 4-Year Follow-up and Real World Data
    EP. 8: Treatment Considerations and Patient Selection for CAR T-cell Therapy in R/R ALL
    EP. 9: Expert Perspectives on Bridging Therapy Strategies Prior to CAR T-cell Therapy
    EP. 10: Sequencing Strategies with CAR T-cell Therapy in Patients with or without Prior Blinatumomab Treatment
    EP. 11: Translating Data Updates from FELIX and ZUMA-3 to the Clinical Practice Setting
    EP. 12: Expert Perspectives on the Potential Impact of Obe-cel on the Treatment Landscape for R/R ALL
    EP. 13: Treatment Approaches with Consolidation and Maintenance Post CAR T-cell Therapy
    EP. 14: Future Perspectives on CAR T-cell Therapy in R/R B-cell ALL
    EP. 15: Frequency, Correlation with Clinical Outcomes, and Risk Factors for Severe CRS and ICANS in CAR T-cell Therapy
    EP. 16: Expert Perspectives in Monitoring and Management Strategies for CRS, ICANS, and Other Long-Term Toxicities Associated with CAR T-cell Therapy
    EP. 17: Logistical and Access Challenges with CAR T-cell Therapy in R/R ALL
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    EP. 18: Strategies and Resources for Overcoming Barriers to CAR T-Cell Therapy
    EP. 19: Role of Multidisciplinary Team & Logistics of CAR T-cell Therapy Administration in the Inpatient or Outpatient Setting
    EP. 20: Key Takeaways and Clinical Pearls in the Treatment of R/R ALL

    Video content above is prompted by the following:

    • What are some resources and/or strategies to help support and solve these logistical challenges?
      • Please comment on different CAR-T patient support programs (lodging, support resources etc.)
    • At your institution, are patients who are eligible for CAR-T cell Therapy discussed at a multidisciplinary meeting to discuss these challenges?
    • Are Apheresis or cell laboratory members, social workers, case managers, nurses, pharmacy involved? If so, what are each discipline roles?
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