My Treatment Approach: HER2+ Breast Cancer - Episode 7

TKI Regimens and Other Novel Approaches in Later Line Treatment of HER2+ mBC Setting

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Vijayakrishna Gadi, MD, PhD, shares his insights on managing patients with HER2-positive metastatic breast cancer who have progressed on second and third-line treatments, stressing the potential benefits of incorporating small molecules, tyrosine kinase inhibitors (TKIs), chemotherapy, and enrolling patients in clinical trials to optimize outcomes.

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    Video content above is prompted by the following questions:

    • For patients who progress through multiple HER2-targeted therapies, when would you consider chemotherapy and what specific regimens?
    • Are there data supporting the use of continuing HER2 blockade with chemotherapy in later lines?
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