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Jason Sicklick, MD, FACS

Articles

Biological Mechanisms of GIST Resistance and Tumor Heterogeneity

March 31st 2025

Experts discuss the biological mechanisms of resistance in gastrointestinal stromal tumors (GIST), differentiating between primary and secondary resistance, and explore how tumor heterogeneity evolves throughout treatment, with implications for long-term management and treatment strategies.

Optimizing TKI Selection and Sequencing Strategies in Advanced GIST Beyond First-Line Therapy

March 31st 2025

Experts discuss optimizing TKI selection and sequencing strategies for advanced gastrointestinal stromal tumors (GIST) beyond first-line therapy, focusing on the latest clinical data, molecular characterization, and insights from recent trials to guide treatment decisions.