My Treatment Approach Beyond the First-Line: Expert Insights on Evidence-Driven TKI Selection and Sequencing in Advanced GIST - Episode 6

INTRIGUE Trial: Key Findings in Second-Line Setting

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Experts discuss the key findings from the INTRIGUE trial comparing ripretinib to sunitinib in the second-line setting, focusing on efficacy endpoints like progression-free survival (PFS) and PFS on next line of therapy, and interpret the patient-reported outcome (PRO) and tolerability data reported in the study.

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    • Please walk us through the key findings from the INTRIGUE trial comparing ripretinib to sunitinib in the second-line setting. What were the key efficacy end points evaluated in this study, and how did ripretinib perform compared to sunitinib on measures like PFS and PFS on next line of therapy? How do you interpret the PRO and tolerability data reported from INTRIGUE?
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