Dr Holtan: Please address the 3 phases of pathophysiology of cGVHD (early inflammation, chronic inflammation and dysregulated immunity, and aberrant repair and fibrosis) and the interplay between them.
How does inflammation affect different organs? And fibrosis?
Dr Ali:After confirmed diagnosis, please share your monitoring routine for patients with cGVHD.
Are there certain symptom scores (eg, Lee skin symptom score) that are associated with better clinical outcomes?
How do you share responsibility across subspecialty to monitor patients? Or other HCPS?