My Treatment Approach: Optimizing Treatment for Chronic GVHD - Episode 2

Navigating Chronic GVHD: Phases of Pathophysiology and Best Practices in Patient Monitoring

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Medical experts discuss navigating chronic GVHD.

Video content above is prompted by the following:

  • Dr Holtan: Please address the 3 phases of pathophysiology of cGVHD (early inflammation, chronic inflammation and dysregulated immunity, and aberrant repair and fibrosis) and the interplay between them.

How does inflammation affect different organs? And fibrosis?

  • Dr Ali:After confirmed diagnosis, please share your monitoring routine for patients with cGVHD.
    • Are there certain symptom scores (eg, Lee skin symptom score) that are associated with better clinical outcomes?
    • How do you share responsibility across subspecialty to monitor patients? Or other HCPS?