First AD

Second AD

Benjamin P. Levy, MD, is clinical director of Medical Oncology at Johns Hopkins Sidney Kimmel Cancer Center at Sibley Memorial Hospital and associate professor of oncology at Johns Hopkins University School of Medicine.

Personalizing Adjuvant Targeted Therapy in Early-Stage NSCLC

Video content above is prompted by the following:

How are you incorporating the ADAURA and ALINA regimens into your clinical practice, and what factors influence your patient selection?

What is your anticipated duration of therapy for patients receiving adjuvant osimertinib or alectinib?

What is the role of ctDNA in early-stage NSCLC, and how may it guide adjuvant therapy decisions? (

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Bridging the Gaps in Lung Cancer: 6 Month Update Winter Lung Cancer Conference 2025

OncLive Insights

Panelists discuss how, in clinical practice, ADAURA (osimertinib) and ALINA (alectinib) are integrated based on EGFR/ALK status, stage, and recurrence risk. Adjuvant therapy duration is typically 3 years. Circulating tumor DNA (ctDNA), minimal residual disease (MRD) from ADAURA (ASCO 2024, Abs 8005) may refine treatment decisions by detecting MRD.