EHA 2024: Updates in the Treatment of CLL    - Episode 2

Testing Practices and Role of High-risk Features to Decision Making in Newly Diagnosed CLL

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Leading chronic lymphocytic leukemia specialists explore strategies for selecting initial treatments, weighing the merits of fixed-duration versus continuous Bruton's tyrosine kinase inhibitor (BTKi) therapy for newly diagnosed patients.

EP. 1: Introducing the Expert Panel on CLL Treatment Updates Live at EHA 2024
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EP. 2: Testing Practices and Role of High-risk Features to Decision Making in Newly Diagnosed CLL
EP. 3: Frontline BTKi Selection
EP. 4: Dr Parrondo’s Frontline CLL Treatment Approach for Pre-existing HTN and Afib
EP. 5: Dr Lamanna Reviews Study Data for 1L Doublet Therapy or Triplet Therapy
EP. 6: Dr Danilov Reviews EHA 2024 Data on the Role of 1L Triplet Therapy in CLL
EP. 7: EHA 2024 Review of Ongoing Trials Evaluating BCL2i/BTKi Combination Approaches
EP. 8: Navigating Treatment Approaches for R/R CLL
EP. 9: How Experts View MAIC Data That was Presented at EHA 2024
EP. 10: BTKi Intolerance in Real-world Practice & Management Strategy
EP. 11: Applying EHA 2024 Data to Switching and Sequencing Treatments for CLL & Impact of Toxicities
EP. 12: Approach to Hypertension Management With BTKi Treatment
EP. 13: Dr Parrondo shares Approach to Managing BTKi Treatment-Related Afib
EP. 14: Navigating BTKi Resistance in CLL with Findings from ELEVATE-RR and ALPINE Studies: Sequencing Approach and Potential Role for Testing
EP. 15: Experts Review Pirtobrutinib Clinical Data and Share its Utilization in Practice
EP. 16: TRANSCEND CLL 004 Data Review and its Impact on Future Treatment Practices
EP. 17: EHA 2024 Updated Data on BTKi Degraders as Emerging Novel Agents in R/R CLL
EP. 18: Dr Parrando Reviews EHA 2024 Data on BTKi Degrader, BGB-16673
EP. 19: Dr Lamanna Shares Perspectives on EHA 2024 Data for the 2G BCL2 Inhibitors in R/R CLL
EP. 20: Review of Data from EHA 2024 of Emerging Novel Bispecific Antibodies
EP. 21: Clinical Pearls and Impacts to Practice from EHA 2024
  1. Dr Davids: What is your general approach to navigating available treatment options in patients with newly diagnosed CLL?
    • In which patients do you consider fixed duration vs continuous BTKi therapy?
    • How do the presence of high-risk features (del17p, TP53 mutations) influence your treatment decision?